Exciting news! I've accepted a job offer at Rockefeller University The Bonilla lab is opening this fall and is hiring at all levels! Interested in exploring RNA structure-function using #cryoEM , biophysics, computational tools, etc? Interested in viral RNAs? Join us in beautiful NYC!

Excited to announce a new preprint: biorxiv.org/content/10.110… We developed a high-throughput method to measure the thermostability of RNA tertiary contacts using DMS chemical mapping and Mg2+ titrations. We believe this method is highly generalizable to many different systems. 1/

Please check out our Reviewed Preprint in @elife. Congratulations to Thuy Ngo & co-authors. Dependence of Nucleosome Mechanical Stability on DNA Mismatches doi.org/10.7554/eLife.…

Are you ready for the ultimate summer experience of a lifetime?
The Kupcinet-Getz International Summer Program at the esteemed Weizmann Institute of Science is now accepting applications! Dive into a 7-week immersive science enrichment program designed for ambitious undergraduate…

Today is Kfir Bibas's 1st birthday.

He was abducted aged nine months.

He has now been a hostage of Hamas for one-quarter of his sorry life.

POLE variants promote genome-wide mutations in polypurine tracts - check out our paper by Daria Ostroverkhova in collaboration with Polina Shcherbakova's lab
cell.com/cell-reports/f…

Interested in the genome and attending #bps24 ? Join the MGO subroup and attend our symposium on Saturday which includes talks by
Mario Halic HalicLab
Emma Morrison Emma Morrison
Alexey Shaytan Alexey Shaytan
Remo Rohs Remo Rohs
biophysics.org/store/products…

How to eat a lot of sugar and not get diabetes? Fruit bats could have the answer. Amazing single-cell bat work by Wei Gordon, Seungbyn Baek, Martin Hemberg and many others.
nature.com/articles/s4146…

You can easily prepare 13C,15N-labeled DNA G-quadruplex, aptamer, and DNAzyme through isothermal amplification. See our JACS paper published in this week.

pubs.acs.org/doi/full/10.10…

Shankar Balasubramanian received the Breakthrough Prize in Life Sciences award - along with David Klenerman and Pascal Mayer - for work revolutionizing DNA sequencing. Watch the full presentation from the Breakthrough Prize ceremony at youtu.be/UQUrLn46yjg.

🎉It's finally out!! We show that intramolecular interactions in IDPs are strong enough to hold in the cell, but flexible enough to respond to cellular volume changes. A labor of love of many people, mainly recent graduate David Moses and Karina Guadalupe. shorturl.at/cdyR2

Check out our latest paper on the transcriptional response to bulky DNA damage! What's new? First: What's true for UV isn't necessarily true for other bulky damages. Second...
life-science-alliance.org/content/7/3/e2…

We have a web interface for predicting DNA cyclizability. Entering a PDB ID shows the preferred bending direction around a protein. Widom 601 DNA has strong and weak sides, and indeed intrinsic bending is toward the nucleosome center for the strong side (LH) only. Plz try it out!

In our new lab preprint, led by Devin Rocks , we introduce the first sex-specific immediate early gene, Egr1! Egr1 opens neuronal chromatin sex-specifically, with consequences for targeted gene expression changes, synaptic plasticity and behavior🧵 👇
biorxiv.org/content/10.110…

DON’T STOP SPEAKING ABOUT THE HOSTAGES!

Men, women, babies, girls, elderly, 129 hostages are still held captive by Hamas in Gaza for over 81 days.

We need them home now!

מחפשת סטודנט.ית לדוקטורט (או פוסט). מחקר מולקולרי וביוכימי בצמחים. אני מאמינה בעבודת צוות ובחניכה איכותית שמטרתם להתקדם יחד ולעשות מחקר ומדע ברמה גבוהה. נכונה לחכות למי שעסוק בימים אלה בהגנה על כולנו. העבודה בעיר הטובה בעולם. אשמח בעזרה להפצת המודעה.

Listen to Adi’s PhD student, Nufar, whose brother is held hostage in Gaza for 81 days. My cousin, Itai Svirsky, is there as well. 129 hostages are still there, most of them are still alive. Help them. Help us. #BringThemAllHomeNow

Releasing our bioRxiv and drug design AI method DrugHIVE for the structure-based design of drug-like molecules, a project led by USC Dept. of Quantitative & Computational Biology USC Physics USC Dornsife College of Letters, Arts & Sciences graduate student Jesse Weller. DrugHIVE enables the exploration of the vast chemical space @USC USC Research.

Check out our new paper: “Intrinsically disordered regions of the Msn2 transcription factor encode multiple functions using interwoven sequence grammars” published Nucleic Acids Res. The work of Vladimir Mindel and Sagie Brodsky. academic.oup.com/nar/advance-ar…