Deep learning and atomistic simulations unveil the conformational dance of RNAs, highlighting RNAs populating plentiful metastable states, to further the understanding of condensate formation. Ramachandran and Potoyan. cell.com/biophysj/fullt…

Read about the cover art for the newly released issue of Biophysical Journal on the BPS Blog: biophysics.org/blog/macrophag…

Special issue call for papers: Materials and Measurement in Mechanobiology. ow.ly/u5gk50RtzFK

Onwudiwe et al. use a fluid shear stress assay to explore the viscoelastic properties of primary brain tumor cells. The findings show distinctive mechanical behavior in malignant human glioblastoma cells, contributing to knowledge of brain tumor mechanics. ow.ly/IvmL50RzI06

In new work, Michel and Lemkul study the properties of a quadruplex:duplex junction, revealing base pair dynamics, electrostatics, and thermodynamic properties. Check it out here: bit.ly/3WptEmi Virginia Tech

Special issue call for papers: Point spread functions—from fluorescence correlation spectroscopy to multiphoton microscopy: Dedicated to Watt W. Webb. ow.ly/KpMp50RtzvJ

Special issue call for papers: Membrane Fusion and Budding. ow.ly/MNFM50Rtzh1

#OPENACCESS : The study unveils the coordination of Zn by all three cysteines in a nucleotide-dependent zinc metallochaperone from a human pathogen. Thermodynamics & mass spectrometry shed light on G-domain folding induced by nucleotide binding. ow.ly/ceVG50Rhe2L

Special issue call for papers: Proton Reactions: From Basic Science to Biomedical Applications. ow.ly/MTPU50RtzaC

A new Computational Biophysics section encourages submission of papers on the development of methods and algorithms rationalizing biological data with biophysical/bioinformatic modeling, simulation, and artificial intelligence. ow.ly/lKOq50R7OcL

#OPENACCESS : This study by Hancock and Datta explores E. coli growth inside hydrogel matrices with defined and highly tunable rheological properties, revealing how rheology modulates microbial physiology on a large, global scale. ow.ly/RRqu50RhcTx

We are once again accepting submissions of Letters! These are short articles (no more than five pages) on diverse areas that report exceptionally important results in an accelerated manner. To submit a Letter, please go to biophysj.org for more information.

A simple two-input, single-locus model of transcription by Dixit et al finds that new logic operations are possible out of equilibrium, expanding the range of cellular decision-making. Check it out here: bit.ly/3PZ0MNA The Institute of Mathematical Sciences Institute of Molecular Genetics

Special issue call for papers: Membrane Fusion and Budding. ow.ly/Nwrh50Rijm3

Special issue call for papers: Proton Reactions: From Basic Science to Biomedical Applications. ow.ly/nYx250Rijfk

THz-spectroscopic evidence reveals hydration water's pivotal role in driving the thermodynamics of the process. This insight opens doors to exploring co-solute effects and designing targeted pharmaceuticals for DNA G-quadruplexes. ow.ly/PRgM50RhcwL

Special issue call for papers: Advances in Mechanotransduction, Dedicated to Frederick Sachs. ow.ly/Ev3950RflhT

Special issue call for papers: Point spread functions—from fluorescence correlation spectroscopy to multiphoton microscopy: Dedicated to Watt W. Webb. ow.ly/GkiX50Rij5u

In the latest New and Notable, W.R. Harcombe explores mechanomicrobiology, highlighting Hancock and Datta’s recent study. Find out how hydrogels unveil the role of rheology in predicting Escherichia coli growth and metabolism. ow.ly/cifw50RhcoU

Special issue call for papers: Materials and Measurement in Mechanobiology. ow.ly/kT8350Rh3ML