Primary ciliary dyskinesia ( #PCD ) is a rare inherited multi-organ condition, which can lead to airway inflammation and infections. Now, scientists led by the The Mill Lab at The University of Edinburgh and the Institut Imagine at Université Paris Cité found what causes PCD. dlvr.it/T6PVp7

How does dynein cycle its conformations and takes one step forward along the MT?
Check out our exciting new results unveiling the atomic details of the conformational space of Reactive Full-length Human Dynein-1, on and off microtubules: biorxiv.org/content/10.110…

Initiation pratique au dosage par chromatographie: découvrez phases, éluants, étalonnage, et devenez un-e pro pour doser une substance UV-active! #HPLC
🧪🔬ow.ly/G81850PIguK

Introducing The MicroRealms Projector! 🎉 A powerful and affordable 50-1000X microscope with an embedded projector, small enough to fit in your pocket.

Live on Kickstarter - get yours now: buff.ly/4b01IJV

#newproduct #launch #microscopy #stem

Call for Postdoc.Mobility. Expand your research experience with a stay abroad. Submission deadline: 2 August 2024. If you would like to find out more about this call, take part in our online information event on 14 May 2024. sohub.io/dvcj

The IECB Institut Européen de Chimie et Biologie is looking for two team leaders, one in organic chemistry and one at the chemistry-biology interface (biophysics, structural biology, cell biology, computational modeling, etc.). Applications from experienced postdocs or senior researchers are welcome

Thrilled our ‘team science’ TUBB4B work is out in Science Magazine led by Daniel Dodd MRC_HGU & Institut Imagine colleagues on how #RareDisease informs on fundamental biology- the ‘tubulin code’ & microtubule diversity within a cell & across tissues! science.org/doi/10.1126/sc… A 🧵/1

Amazing iU-ExM gel at SLN - ICFO still fluorescent after one week in my backpack, definetly not bad 😁
Great staining of endoplasmic reticulum and tubulin Marine Laporte and Vincent LOUVEL
#EMBOExM #UExM

Yay! Our preprint on affordable super-resolution tool for #Toxoplasma chronic stage is out!
Leveraging #ExM to explore cysts wasn't easy, and I'm excited about the possibilities this opens up for Toxo parasitologists.
Joanna Young lab
biorxiv.org/content/10.110…
#Microscopy #Science

April has been a busy month for the tiny tubulin TUBB4B - different missense variants in left-handedness (doi.org/10.1038/s41467…) to #RareDisease blindness or lung disease or both (science.org/doi/10.1126/sc…). Do #ciliadoitall

Great to see this story out led for The Mill Lab ! A truly multidiscplinary exploration of the impact of tubulin isoforms on ciliopathies - paves way for more studies uncovering hidden biology of protein isoforms. Well done to everyone involved especially Daniel Dodd

🎭 We were proud to host 'Coffee Machine' by Specta(c)tor, transforming discussions on #workplaceequality at #FacSciUNIGE .

This interactive theatre forum took on #sexistdiscrimination in academia with real audience engagement. Thanks to all who joined and contributed! 💫

📣 Our EMBO practical course #EMBOExM last week even produced two poster prize winners 🥳
Congratulations to
🏅 Jana Leuenberger, University of Bern, Switzerland
🏅 Yong Heng Phua, Okinawa Institue of Science and Technology Graduate University, Japan

Participants and trai...

The program of the Plant and Microbial Cytoskeleton GRC is online: grc.org/plant-and-micr…

Lots of opportunities for short talks!

Re-tweet and submit your abstracts!

#cytoskeleton #actin #microtubules #septins
#yeast #plants #bacteria #archaea #protists

Registrations now starting to come in for Cilia2024. Reminder that the early bird deadline is May 31. Also, if you are considering room share to reduce hotel costs, you can post your interest and connect with attendees on the website's bulletin board. cilia2024.ie/topics/

Our new mini review about the molecular architecture of the ciliary transition zones is out. Mercey Olivier & Souradip Mukherjee discuss recent cryo-ET and super-resolution work in this field, as well as the structural and molecular variability of TZ.
sciencedirect.com/science/articl…

If you want to see a beautiful U-ExM application for imaging whole mosquito organs, check out this preprint (and this image 🤩🤩🤩 )

Centrosome Pre: A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture dlvr.it/T5nJx3

Our paper on preparing infected mosquito tissues for U-ExM is now up as a pre-print! We validate that method preserves both anatomical and ultrastructure, and have a protocol for anybody who wants to give it a try! Joel Vega Rodriguez Sabrina Absalon Thiago Luiz, PhD. biorxiv.org/content/10.110…

🔬 The EMBO Practical Course 'Ultrastructure expansion microscopy' came to an end yesterday 🌟
Thanks to the participants and organisers of #EMBOExM for their invaluable contributions to the success of this course 🙏

Wishing you all the best in your future endeavors ✨