The Genome Browser is experiencing issues and our system administrators are working to bring the site back as soon as possible. Please use one of these UCSC Genome Browser mirror servers in the meantime:

Europe mirror: genome-euro.ucsc.edu
Asia mirror: genome-asia.ucsc.edu

We are pleased to announce the release of the gnomAD (Genome Aggregation Database) v4 constraint metrics for hg38 and the addition of a non-cancer filter for the hg19 Exome Variants v2.1.1 and the hg38 Genome Variants v3.1.1 tracks.

Learn more at bit.ly/gnomAD_032624

We are happy to announce the new Human Prediction Scores super track for the GRCh37/hg19 assembly. This super track currently includes the BayesDel track, which can be used for clinical variant classification research.

More information is available at bit.ly/BayesDel

We are excited to announce the new JASPAR 2024 tracks for hg19, hg38, mm10, and mm39 which represent genome-wide predicted binding sites for transcription factors with binding profiles in the JASPAR CORE collection (JASPAR database).

Learn more at bit.ly/JASPAR2024

We are happy to announce the release of the AbSplice scores track for the human genome, GRCh38/hg38. The scores represent the probability that a given variant causes aberrant splicing in a given tissue.

Learn more at: genome.ucsc.edu/goldenPath/new…

DECIPHER has a new handle! To better reflect our URL and to make it easier to find us, we are now
@deciphergenonomic

We are happy to announce the release of the All GENCODE tracks for hg19, hg38, and mm39. These tracks correspond with the Ensembl 111 release.

Learn more about the release from the following news post: bit.ly/4bDSxj3

We are happy to announce an update to the Variants of Concern track to include the latest WHO-designated variants of concern (VOC) for the SARS-CoV-2 genome.

Learn more about this release at:
genome.ucsc.edu/goldenPath/new…

The CRISPR Targets track is now available for human (T2T CHM13v2.0).

The CRISPR Targets track shows the DNA sequences targetable by CRISPR RNA guides using the Cas9 enzyme from S. pyogenes (PAM: NGG) over the entire human genome.

Learn more at:
tinyurl.com/3ce6jxea

Quick update, all services should be back online. The only exceptions are some BLAT servers that are still coming back slowly, notably hg19. It should be back in the next hour or so.

Thank you all for your patience while we addressed the situation.

Most of our resources are back online. The last few items will be out BLAT and isPCR servers. Those are being restarted and the full process will take a few hours.

We are currently getting some severe weather in Santa Cruz, CA. It is affecting many of our systems, and parts of our site are down. Our euro mirror (genome-euro.ucsc.edu) is mostly functioning. We apologize for the inconvenience and hope to be back online soon.

We are happy to announce the release of the AVADA variants track for human (GRCh38/hg38).

Mouse-over the variants to show the gene, variant, first author, year, and title.

Learn more at: tinyurl.com/475a7wye

We are proud to announce a new hg38 track group consisting of Human Pangenome Reference Consortium data. In this first release, there are tracks displaying features and variations of HPRC results compared to hg38, as well as alignment tracks.

See the full announcement: bit.ly/HPRCdataInUCSC…