Searching for women speakers working on the cutting-edge of GRCRs & G protein signaling - look no further! Check out the #GPCRladies website list of PIs, Fellows and Postdocs. Thanks for organizing Silvia Sposini TasteLabHUJI, Moran David! DrGPCR
gpcrladies.com/about/

Spatial Control of Receptor Dimerization Using Programmable DNA Nanobridge pubs.acs.org/doi/10.1021/ac…

Aptamer-based double-stranded DNA bridge acting as “DNA nanobridge”, which regulates receptor dimerization by changing the number of bases.

A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes dlvr.it/SqmZ3l

Yes - huge thanks and congratulations to Martine and Andrew for a superb meeting!

Passing Montreux. 16/6/23. No smoke visible on water. Can confirm, though - it is still on Lake Geneva shoreline 🤟

And so begins the journey Home from the molecular #pharmacology #GRC . Fabulous week of great science in stunning location. So lovely to catch up with collaborators and friends.

Attending the GRC in Molecular Pharmacology, I’ve noticed many female ECIs haven’t signed up for GPCRladies - sign up using the following links: Postdocs gpcrladies.com/postdoc

So excited to share our new publication in Nature Immunology! We leveraged new bioinformatics pipelines and a synthetic biology approach to identify a novel GPCR-Gs-PKA immune checkpoint promoting T cell exhaustion and cancer immunology failure. nature.com/articles/s4159… Eytan Ruppin, MD, PhD

I wrote a review!

Get yourself a PDF of it here:

authors.elsevier.com/sd/article/S09…

The main paper of my PhD, our smFRET study of sub-millisecond structural dynamics in A2A adenosine receptor (GPCR) is out in Communications Biology ! 🥳🥳🥳

nature.com/articles/s4200…

After two years from #preprint to publication I have no words

Sisyphus turned into Heracles, finally!

Exciting ~5yr postdoc opening in my lab to investigate heart disease

Aim: CRISPR snoRNAs in hiPSCs to unveil mechanisms of hypertrophic cardiomyopathy & develop new treatments

Closing date 18 April. Interested? See shorturl.at/jwCG9

Mandy Peffers Nottingham Research University of Nottingham Biodiscovery Institute

Finally out: mScarlet3
A brilliant and fast-maturing red fluorescent protein.
Congrats to the teams of Dorus Gadella and Antoine Royant!
nature.com/articles/s4159…

In our latest review, doi.org/10.1186/s40580…, we discussed recent technology development of spectroscopic single-molecule localization microscopy #SMLM #sSMLM , and its applications to biology and chemistry. We emphasized the impact of #sSMLM to single-particle tracking #SPT .

So happy and honored to be part of this incredible contribution to the field, led by Valerie Panneels and Gebhard F X Schertler
Ultrafast structural changes direct the first molecular events of vision
nature.com/articles/s4158…
Congrats all authors!

Time-resolved cryo-EM of G protein activation by a GPCR biorxiv.org/content/10.110…

Optimized two-color single-molecule tracking of fast-diffusing membrane receptors
biorxiv.org/content/10.110…

Pharmacologists! Come and have a brilliant time with me!

New business idea - I'm going to set up a dating agency for poultry 🐔 ❤️

Might seem a bit tangential but just trying to make hens meet...

#groan #dadjoke

UK spring in a nutshell. Some stunning showers, sun and 🌈 This over Stanton but Dale, Derbyshire on Friday #StormHour #ThePhotoHour

Happy to see the work of new GCaMPs finally out! jGCaMP8, your MUCH IMPROVED GCaMP! We have been using it for many months now and for us it has been amazing. Congrats LoogerLab et al! nature.com/articles/s4158…