Marieke Oudelaar(@MariekeOudelaar) 's Twitter Profileg
Marieke Oudelaar

@MariekeOudelaar

Lise Meitner Research Group Leader @mpi_nat. Genome Organisation and Regulation. She/her.

ID:1057218495530913792

calendar_today30-10-2018 10:31:46

389 Tweets

1,3K Followers

466 Following

Emma Farley 🇪🇺(@EKFarley) 's Twitter Profile Photo

Pinpointing causal variants that disrupt development. So proud of the amazing team on this epic enhancer genotype-to-phenotype study. Well Done, Fabian Lim, Joe Solvason, Genevieve Ryan, Sophia Le, Granton Jindal, Paige Steffen and Simran Jandu!!! doi.org/10.1038/s41586…

Pinpointing causal variants that disrupt development. So proud of the amazing team on this epic enhancer genotype-to-phenotype study. Well Done, Fabian Lim, @JoeSolvason, Genevieve Ryan, Sophia Le, @granton_jindal, Paige Steffen and Simran Jandu!!! doi.org/10.1038/s41586…
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The Groth Lab(@GrothLab) 's Twitter Profile Photo

Ready to give your lab a green makeover?🌿Explore our insights on making research more sustainable in this World view by Kathryn Wattam, Matt Todd and Anja Groth 🇺🇦 in Nature Cell Biology Let's take steps towards a greener scientific future!💚🔬 rdcu.be/dv82V

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Tineke Lenstra(@tinekelenstra) 's Twitter Profile Photo

Check out our latest review in Trends in Genetics where we compare timescales of transcription regulatory steps (input) and transcriptional burst kinetics (output) to better understand the mechanisms of transcription regulation. doi.org/10.1016/j.tig.…

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Akis Papantonis(@AkisPapantonis) 's Twitter Profile Photo

2024 starting off on the right foot: Our preprint on the repurposing of a small molecule inhibitor to induce homogeneous and SASPless replicators-like senescence to human cells is now out in Aging Cell.

onlinelibrary.wiley.com/doi/10.1111/ac…

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Romain Koszul(@rkoszul) 's Twitter Profile Photo

Interested in transcription & chr. folding?
A reminder of our work w/ O Espeli (or jump to nature.com/articles/s4159…)
Charlie Reid (Cockram) used a trick to activate a single transcription track along a transcriptionally inactive E. coli genome.
The result? a TID! (Transcription Induced Domain)

Interested in transcription & chr. folding? A reminder of our work w/ O Espeli (or jump to nature.com/articles/s4159…) @chreid86 used a trick to activate a single transcription track along a transcriptionally inactive E. coli genome. The result? a TID! (Transcription Induced Domain)
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Aydan Bulut-Karslioglu(@bulutkarslioglu) 's Twitter Profile Photo

2nd episode...
How do the embryos remain alive in the dormant state? Our Vera van der Weijden showed that they completely switch the metabolic profile and use lipid reserves. Now online as post-review publication 10/ nature.com/articles/s4155…

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Lars Jansen(@larsjansenlab) 's Twitter Profile Photo

A new chapter in our quest to understand long-term transcriptional memory! biorxiv.org/content/10.110…
A unique chromatin signature remembers past gene activation for multiple cell doublings without the signal. Fascinating work by Pawel Mikulski and our team!

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Wei Xie(@xielablife) 's Twitter Profile Photo

Very happy to share our new paper on how SOX2 instructs pluripotency program transition in vivo in mouse E3.5-E7.5 embryos. Spearheaded by our super team: Lijia Li, Fangnong Lai, Xiaoyu Hu and Bofeng Liu. Wonderful collaboration with Amy Ralston. (1/n)
science.org/doi/10.1126/sc…

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StarkLab(@stark_lab) 's Twitter Profile Photo

Today, we - StarkLab and Eileen Furlong lab (@EMBLheidelberg) - report the design of 40 synthetic enhancers for 5 tissue types in fruit fly embryos, in vivo. With only a few hundred enhancers per tissue for training, we adopt a stepping-stone transfer-learning approach: (5/N)

Today, we - @stark_lab and @Eileen_Furlong lab (@EMBLheidelberg) - report the design of 40 synthetic enhancers for 5 tissue types in fruit fly embryos, in vivo. With only a few hundred enhancers per tissue for training, we adopt a stepping-stone transfer-learning approach: (5/N)
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Ibrahim I. Taskiran(@ibrahimihsan) 's Twitter Profile Photo

Exciting news! Our latest research on 'Cell type directed design of synthetic enhancers' has been published in nature. We've harnessed deep learning to design enhancers with cell-type specificity. Find our paper here: nature.com/articles/s4158…. Highlights below: [1/n]

Exciting news! Our latest research on 'Cell type directed design of synthetic enhancers' has been published in @Nature. We've harnessed deep learning to design enhancers with cell-type specificity. Find our paper here: nature.com/articles/s4158…. Highlights below: [1/n]
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Marieke Oudelaar(@MariekeOudelaar) 's Twitter Profile Photo

Please apply if you are interested to join our team MPI for Multidisciplinary Sciences in Göttingen (Germany) as a PhD student and to study the 3D organisation and regulation of the genome!

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Gebhardt Lab(@GebhardtLab) 's Twitter Profile Photo

Happy to share our new preprint about the chromatin binding kinetics of cohesin and CTCF during zebrafish embryogenesis by Jonas Coßmann (SMT, Gebhardt Lab) and Pavel Kos (simulations, Luca Giorgetti). Thanks also to Vassiliki Varamogianni-Mamatsi (@AkisPapantonis).

Happy to share our new preprint about the chromatin binding kinetics of cohesin and CTCF during zebrafish embryogenesis by Jonas Coßmann (SMT, @GebhardtLab) and Pavel Kos (simulations, @LucaGiorgetti). Thanks also to Vassiliki Varamogianni-Mamatsi (@AkisPapantonis).
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Christa Bücker(@chribue) 's Twitter Profile Photo

New Preprint from the lab! We are exploring enhancer collaborations and found some really cool stuff! biorxiv.org/content/10.110…

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Effie Apostolou(@efapostolou29) 's Twitter Profile Photo

Just out NatureStructMolBiol! Our work on mapping 3D enhancer networks in early embryonic lineages and introducing the 3D-HiChAT model for predicting transcriptional behaviors and functional hubs of gene coregulation. rdcu.be/dsN4W

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jop kind(@kind_jop) 's Twitter Profile Photo

Are you interested in mapping six or more chromatin profiles in single cells? With a method that is unrelated to any of the current strategies? Our work on developing MAbID is out. Amazing Job by Silke Lochs and Robin H. van der Weide ! nature.com/articles/s4159…

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Marc A. Marti-Renom(@mamartirenom) 's Twitter Profile Photo

🚨🚨Dear friends! We have two openings in the lab!!
Postdoc in 3D modeling👉🏻 cnag.eu/jobs/postdoc-s…
Front-End developer 👉🏻 cnag.eu/jobs/front-end…
Please, retweet 🔄
Join us!!! 😁

🚨🚨Dear friends! We have two openings in the lab!! Postdoc in 3D modeling👉🏻 cnag.eu/jobs/postdoc-s… Front-End developer 👉🏻 cnag.eu/jobs/front-end… Please, retweet 🔄 Join us!!! 😁
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Aniek Janssen(@AniekJ) 's Twitter Profile Photo

Happy to share the first pre-print of our lab where we find that DNA repair in constitutive heterochromatin depends on specific histone acetylation activities. Thank you especially to Apfrida Kendek, Arianna Sandron and Jan Paul Lambooij for their hard work!

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deWitLab(@deWitLab) 's Twitter Profile Photo

Our paper on patient-specific MYC enhancers in malignant rhabdoid tumors was just published in Nature Communications Please the link here: nature.com/articles/s4146…
Excited to see our fundamental research on 3D genome folding help to understand this highly aggresive and deadly disease.

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Asifa Akhtar(@AsifaAkhtar1) 's Twitter Profile Photo

Ever considered that the loss of your favorite epigenetic factor might impact gene expression in an allele-specific manner? Our new study shows allele-specific gene regulation by the chromatin regulator MSL2.nature.com/articles/s4158…

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