NEW: Bird flu may have been circling in cattle as early as December.
1. USDA announced in March.
2. In April USDA shared only partial data, making it hard to track. The last thing we need is less data.
3. USDA says farmers aren’t letting them fully test
nature.com/articles/d4158…

At ASPLOS in beautiful La Jolla listening to Ilkay Altintas, Ph.D. and her insights on the convergence of #AI and #HPC

6/ A dolphin in Florida was found to have H5N1 avian flu with a S246N neuraminidase substitution leading to reduced inhibition by neuraminidase inhibitor oseltamivir (i.e. resistance to Tamiflu).
nature.com/articles/s4200…

Norway - H5: 'It is the first time that bird flu has been recorded in a walrus,' Lydersen of the Norwegian Polar Institute flutrackers.com/forum/forum/eu… h/t Pathfinder

This study uncovers the intricate allosteric regulation of Brr2 spliceosome helicase, shedding light on the surprising role of snRNAs as an allosteric regulator. Alessandra Magistrato Francesco Guidarelli mattioli Andrea Saltalamacchia #RNA #splicing #allostery
go.acs.org/97V

Here’s the problem. 99% of climate scientists agree the climate is warming and humans, mainly due to the burning of fossil fuels, are the cause. BUT in the US, only 55% of people know that virtually all experts agree. Called the consensus gap, fueled by deliberate disinformation.

It’s not only they’re 2 shot vaccines, they’re made in eggs & cells w/ many limitations due to yield & immunogenicity. They will require additional of adjuvant and will take many months for supply ramp up.

Vietnam waited 2 years for flu vaccine in the 2009 H1N1 pandemic.

We

The postmortem exams of cats who died of #H5N1 #BirdFlu on dairy farms show devastating effects on the heart, lung, eyes, & brain.

‼️Do not consume raw (unpasteurized) dairy products.

#MedTwitter , 👀 at the screenshot. #AvianFlu #IDTwitter

wwwnc.cdc.gov/eid/article/30…

This is exactly what I’d expect from high path avian influenza H5N1 in many mammals. It’s a deadly virus. Any attempts to minimize the threat of this virus are irresponsible.

This virus can change easily, can spread swiftly, and cause great harm. There has never been such

'early release of a publication as a preprint correlates with a significant citation advantage of ~20%...we do not find a citation advantage for sharing code' via Iain Hrynaszkiewicz arxiv.org/abs/2404.16171

🚨 APOBEC3B (A3B) is a major source of🧬mutation in cancer

The active site is like Teflon (not much binds) BUT Ozlem Dmr discovered a druggable allosteric site 👀

Experiments by Dan Harki Katherine Jones The Harris Lab 💪

biorxiv.org/content/10.110…

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations biorxiv.org/content/10.110…

Dr. Prather has been recognized with the #NASAward in Chemical Sciences for the impact of her work in understanding our climate and global health and for her leadership in helping us navigate the pandemic. Watch her speech at the ceremony. We're so proud, Kim! Kimberly Prather, Ph.D.🏅

Accepting the 2024 NAS Award in Chemical Sciences is #NASmember Kimberly A. Prather of UC San Diego and Scripps Institution of Oceanography for her pioneering research on aerosols. #chemistry #NAS161 #NASaward

Watch live: ow.ly/pWZk50RqemO

After 3 years since #Martini3 's publication, it's time to assess the current state of the #Protein model, scrutinized by the molecular modeling community. Take a look in the pre-proof of this mini-review just published in BBA: sciencedirect.com/science/articl…

Nice article looking at humidity-induced phase transformations of sub-micron model respiratory aerosol and growth media.
They studied similar systems as we’ve studied in the past, and saw similar outcomes despite using much smaller particles.

pubs.acs.org/doi/abs/10.102…

This is a great opportunity for PhD career stage researchers to get a comprehensive hands on workshop in CryoEM thanks to Wellcome and iNEXT-Discovery for providing funding and foresight to continue our development of training options at eBIC and Diamond Light Source

The FLiRT variant KP.2 begins its takeover for Covid cases in the US, now accounting for 1 in 4 cases
covid.cdc.gov/covid-data-tra…