Stern-Ginossar lab
@SGinossarLab
Virus-host interactions @WeizmannScience
ID:1057972027917766656
http://www.weizmann.ac.il/molgen/ginossar/ 01-11-2018 12:26:02
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Extraordinary claims require extraordinary evidence… In collaboration with computational biology experts Pavitra Roychoudhury and Dan Depledge we conclude that the claim that HSV establishes latency in immune cells is not supported by the underlying datasets
journals.asm.org/doi/10.1128/jv…
So stoked to be sharing this! New proteomics map of human subcellular architecture. CRISPR + organelle IP mass spec at scale. Check out pre-print biorxiv.org/content/10.110… and organelles.czbiohub.org. 🙌 to fantastic team Chan Zuckerberg Biohub Network SF & collabs! 1/2
Now out Cell Reports -- we find striking differences between viral proteins that are presented on class I and class II HLAs, resulting in distinct targets for killer and helper T cells. cell.com/cell-reports/p…
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New paper alert
After more than 15 years in the field this is my first paper in JVirology Editors
My student Alina Shitrit had led this project as part of Ph.D, with our collaborators Moriah Szpara is at BlueSky @szparalab.bsky.social Nir Drayman Weitzman Lab Savas Tay and more
journals.asm.org/doi/10.1128/jv…
Many components of the eukaryotic immune system seem to have a bacterial origin in anti-phage defense.
In this Opinion Trends in Immunology, I discuss recent findings on such conservation of immune components and suggest next steps in the field⬇️
sciencedirect.com/science/articl…
✂️🧬 #CRISPR tool pre-print 📣: protoSpaceJAM.czbiohub.org for insertional knock-in. Streamlined design of gRNA, HDR donor & NGS genotyping primers. #opensource + documented code base. Tour de force from Duo Peng + colleagues at Chan Zuckerberg Biohub Network 👏 biorxiv.org/content/10.110… 🧵1/n
wschneider and I are happy to announce the 6th series of the Systems Virology Journal Club! ✨
Join us to learn about the exciting research at the intersection of virology and systems biology.
Registration (free): forms.gle/edTyLwR8jWkhrR……
Webpage: shiraweingartengabbay.com/systems-virolo…
The in vivo #RNA binding proteome atlas is here!
Meeli Mullari and Nicolas Fossat use our new #RBP #brain atlas to demonstrate deregulation of RBM5 splicing in #Huntington 's disease. In Nature Communications with Nielsen Lab Agnete Kirkeby Niels Skotte CPRatUCPH
rdcu.be/dhf0Y