A subset of CD8 T cells with a terminally exhausted epigenetic profile expressed IFN-γ, granzymes, and perforin in bone marrow Science Immunology
Congrats Simone Minnie! Hill Lab Scott Furlan
science.org/doi/10.1126/sc…

So, seqspec has been published. This is a good opportunity to remind everybody that your count matrix, R object, h5ad etc are NOT your raw data. Raw data are fastq files which are only useful when you know the content of your reads. Then ... 1/7 academic.oup.com/bioinformatics…

Single-cell immune repertoire analysis Nature Methods
nature.com/articles/s4159…

Congratulations to our very own, Simon for passing his qualifying exam! 🎉🎊🎉

Very excited to see our work wildDISCO at the cover of Nature Biotechnology nature.com/articles/s4158…

What a fabulous time it's been to visit Stanford University and meet the outstanding fellows, trainees, and faculty! Thank you dearly for this invitation.

🔬 Investigators generated 3D skin #organoids using bioengineered MSC-derived keratinocyte-like cells and fibroblasts to evaluate their efficacy in type 2 #diabetic transgenic 🐭 mice.

Follow 👣 the link to learn more.

🔗 bit.ly/3Q1nCnF

In a new Review, scientists discuss how resident tissue #macrophages go beyond immunity to keep organs thriving. Ragon Institute HHMI NEWS scim.ag/6zW

As my lab develops Seurat, I wanted to share some thoughts on the important Seurat and scanpy package selection preprint from Joseph Rich/Lior Pachter 🧵

Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles nature.com/articles/s4158… #journals #feedly

We don’t know much about how T cells—the immunological powerhouses—change as we age. But not for long. Learn how researchers used multimodal #singlecell analysis to capture T-cell variability across the age spectrum & uncover a novel subpopulation: nature.com/articles/s4159…

Thrilled to visit Stanford University and present our latest work on wound regeneration Stanford University_MCP! #SyntheticRegeneration

Memory genes are enriched in CAR T cells that persist and control tumors in patients. But which transcription factors drive beneficial memory programs?

We answer this in our lab’s first paper in nature led by Alex Doan Kat Mueller, PhD Andy Chen. 1/

nature.com/articles/s4158…

Our paper 'The landscape of biomedical research' is out in Patterns journal! Great job by Rita González Márquez.

cell.com/patterns/fullt…

Amazing interactive explorer by Ben Schmidt / @[email protected] from Nomic AI: static.nomic.ai/pubmed.html

For details see my original Twitter thread: twitter.com/hippopedoid/st….

'A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility'
nature.com/articles/s4155…

Now Online Fibroblast and myofibroblast activation in normal tissue repair and fibrosis dlvr.it/T5FQMp

Enjoying the stunning view of #Eclipse2024 in NYC!

I appreciate this paper from Joseph Rich/Lior Pachter on the importance of package selection for scRNA-seq: biorxiv.org/content/10.110…

We agree - as we release new versions of Seurat, we make changes, which means that some results will change (and hopefully improve!) for users

Beyond a literal earthquake shaking things up in NYC, we had an absolutely electrifying seminar from Dr. Chrystal Ama Starbird PDB Depositer about her work on Tam receptors Columbia Vagelos College of Physicians & Surgeons. It was such a joy hosting you! #ShakeUpSeminar #SeismicImpact

It was so wonderful to see your lab and the amazing department it’s housed in. I really enjoyed speaking with students in your department as well! Thank you for having me: I had a wonderful visit despite the earthquake 😁🙏🏾