👇🏾 Worth reading

How do yeast adapt to nutrient stress? Lysine auxotrophs evolve & acquire OrgS mutations and utilize GSH. Seminar by Sonal Shou Group UCL in DBS TIFR India

Last meal at IBRO Nepal school a Nepali thali. Not pictured a bowl of yogurt/curd.

Participants in IBRO - International Brain Research Organization Nepal School. A wide introduction to neuroscience from fundamental research to clinical studies.
Lead organizer Dr Sunil Dhungel.

Non-invasive brain stimulation (rTMS) to retrain the brain in cerebral palsy children. Meena Gupta AmityUniversityNoida in IBRO - International Brain Research Organization Nepal School

Lack of sleep has social impact. Sleep gating by motivational arousal depends on adenosine & dopamine. Nucleus accumbens VP circuit contributes to slow wave sleep. NAc astrocyte activation induces SWS via adenosineR. Michael Lazarus IIIS （国際統合睡眠医科学研究機構） Tsukuba U in IBRO - International Brain Research Organization Nepal School

Transcranial magnetic stimulation where magnetic fields to electrical stimulation of nerves, have to monitor side effects of seizures & headaches. Suggests use of TMS in a variety of cases eg post-stoke pain, PD Dr Lekhjung Thapa, MD, DM (Neurology) Natl Neuro Cntr Nepal in IBRO - International Brain Research Organization Nepal School

Rare genetic disorders in Sri Lanka DMD, Huntingtin, autosomal dominant ataxia (consanguinity due to need for care support), SMA & pharmocogenomic variations in drug responses in different populations Vajira HW Dissanayake U of Colombo in IBRO - International Brain Research Organization
Nepal School

Genetic pathways for thalamocortical development and role SNARE vti1a/vit1b in neuron degeneration. @AjayaJangKathmandu Center for genomics (KCGRL) in@IBROorg

Developing personalized early detection for Alzheimer's Disease & other neurodegenerative diseases using brain imaging to identify changes in neural networks. Higher free water associated w/ longitudinal cognitive decline. Juan (Helen) Zhou NUS in IBRO - International Brain Research Organization Nepal School

Airport art Tribhuvan International Airport at Kathmandhu Nepal airport coming to an IBRO - International Brain Research Organization school. IBRO is absolutely fabulous at supporting neuroscience training & education around the world (esp in countries with a small science footprint).

Interesting study Aakanksha Singhvi on mechanical input for cell architecture.

Was interesting to attend a meeting with a large number of clinicians & people working with data collected from patients. #AAICNeuro NIMHANS, Bengaluru

How genomic variation contribute to brain str & fn in healthy aging & neurodegenerative disease in diverse populations. Genetic risk factors in AD & FTD is still not known-we can explain almost half. Jennifer Yokoyama UCSF MAC in #AAICIndia NIMHANS, Bengaluru

Several brain disorders are unique to humans. Points out several limitations from rodents to organ-on-a-chip. Makes a strong case for brain banking. Asia has 60% of the world population with 4 brain banks, India has 1. Anita Mahadevan NIMHANS, Bengaluru in #AAICIndia

Neurosurgery is a craft learnt as an apprentice. Developing paradigms for surgery including risk, order of surgical tasks to develop cognitive robotics for carrying out surgery and objective means to measure surgical skill. Vikas Vazhayil NIMHANS, Bengaluru in #AAICIndia

Complex phenomena may not be explained by reductionist approach eg weaving as embodied cognition. Also dive in knowledge/ways of knowing & ownership of knowledge. Vivek Oak, Handloom Futures Trust in #AAICIndia NIMHANS, Bengaluru

1/100 children in India are blind, 40% are treatable. Presents data on rewiring & long critical period in the visual pathway even for blind 20yr olds after corrective surgery. Tapan Gandhi IIT Delhi in #AAICIndia NIMHANS, Bengaluru

Education, physical activity (never too late to start), social engagement, hearing loss, TBI, obesity, hypertension, diabetes, depression, air pollution, alcohol consumption, smoking & others imp for resilience/reserve for dementia Faheem Arshad NIMHANS, Bengaluru in #AAICIndia

Anti-amyloid treatments for AD, hope or hype? New generations of anti-amyloids are performing perhaps in part due to higher dose. However only some sub-groups show improvement. Durjoy Lahiri Institute of Neurosciences Kolkata in #AAICIndia NIMHANS, Bengaluru