Within 24hrs I got an NOA and two paper rejections… that’s how bivalent genes must be feeling!!! Lesson learned: Don’t wait to celebrate. Next disappointment is just around the corner… #PIlife

Interested in 3D epigenomics? Join this #hackathon organized by 4DNucleome students and postdocs, w/ projects from the groups of William Stafford Noble, Yun Li, Dariusz Plewczynski, Yin Shen, LomvardasLab, Geoff Fudenberg, Christina Leslie, Katie Pollard, and me. March 18-21, 2024 in Seattle University of Washington

👇👇👇wonderful opportunity in our neighboring lab! Check out their amazing research and apply!!!

Thank you Weill Cornell Medicine so much for featuring our recent work NatureStructMolBiol on the mapping and modeling of 3D enhancer-promoter networks in early embryonic lineages and our discussion about the potential implications in other physiologicaL or pathological cell fate decisions.

Congratulations Dr. Murphy!!!

If you attend #ASH23 don’t miss out Laurianne Scourzic poster! She will present exciting findings identifying and characterizing a physiologic, transient, plastic, stem-like state in mature B and potential links to lymphoma! Amazinh collaboration with Melnick Lab Weill Cornell Medicine Meyer Cancer Center nick

Great research opportunity under a great mentor!

Hamas is pure evil. The attrocities we saw and experienced the last days cannot be unseen, undone or forgotten. I'm devastated. But please, I beg you stop propagating violence and hatred. STOP the killing and suffering of innocent people. We MUST push for another solution. PLEASE

As always, amazing speakers lineup! Every year I look forward to this!

My first #NCI grant is finally here! Great collaborative effort with Melnick Lab on a project spearheaded by Laurianne Scourzic! We are so excited for this project and it’s potential impact both in GC biology and lymphoma. Stay tuned for more!

A wonderful woman and dear friend was the victim of a shark attack while swimming in Rockaway Beach, NY. She has 5 planned surgeries and a huge battle ahead! Her daughter organized a gofundme. Please share or contribute if you can!!!

Read more here gofund.me/f56e6558

Congratulations Rehne, Dr. Danwei Huangfu and team!!!

Very excited for the first machine learning model from our lab, named 3D-HiChAT developed by Alexander, that enables prediction of 3D complex regulatory relationships, including enhancer hierarchies and 3D hubs that control gene coregulation.

So proud of you Jiexi Li! Incredible work! So happy for everything you have accomplished and looking forward to your next steps!

Beautiful work from Julian Pulecio and Dr. Danwei Huangfu using a CRISPRa screen during hESC differentiation to discover competent developmental enhancers. Another great collaboration with Dr. Danwei Huangfu group which is on fire 🔥 🔥 🔥 this year…!!!

I am really happy to finally share the preprint of our work unraveling a new class of regulatory regions distinct from enhancers that confer hESCs with the competence to rapidly activate the expression of lineage genes🧬 biorxiv.org/content/10.110… #stemcells #epigenetics #CRISPR