If you haven't been to this before please consider coming along. The meeting has been running since 2012 and has been continually excellent.

Fun fact: did you know that ~10% of random DNA sequences have promoter activity? Much more fun to see it directly under a microscope!

If you like gene regulation and want to join a stimulating international environment - with cutting edge facilities - top healthcare and family benefits. Join us for a post-doc EMBL - funded by ERC embl.org/jobs/position/…

PhD position open on lcRNA and phase separation in the lab of our collaborators Isabel Chillón and Robert Feil IGMM-Montpellier in sunny Montpellier. Great project, great lab, great place. Go there! More info here: adum.fr/as/ed/voirprop…. Or get in touch with Isabel directly!

You have perturbed TFs (for example disease vs healthy) and genome-wide H3K27ac data, what TF activity tools would infer the perturbed TFs that are more likely to be validated?

According to our results, the top 3 tools: RcisTarget, MEIRLOP and monaLisa

biorxiv.org/content/10.110…

Thanks for the highlight Grant! All the credit to Jane Xu Herbert Irving Comprehensive Cancer Center Columbia Stem Cell Initiative (CSCI) — but the best is yet to come!

Great collaboration with Dr Zoë Waller and Dr Ke Li in Exeter! Hope it will benefit the community 😊 iM-Seeker: a webserver for DNA i-motifs prediction and scoring via automated machine learning academic.oup.com/nar/article/do…

A great opportunity available for bioinformatics scientists to explore epigenetics in our lab. Manchester Cancer Research Centre UoM Biology, Medicine and Health Division of Molecular and Cellular Function UoM Manchester Breast Centre

jobs.manchester.ac.uk/Job/JobDetail?…

Join us for your #PhD or #MDPhD if you are interested in exploring how networks of transcription factors & chromatin modifiers can time development by generating transcriptional oscillations. Apply here 👇

Excited to finally share my work with Charles Danko on the regulatory syntax governing transcription initiation and training genomic DL models on diverse genomes. doi.org/10.1101/2024.0…. Blurb thread below: 0/8

Glad that our sequence model of promoters in human genome is now published in Science Magazine. Check out the paper for a deep dive into the sequence basis of transcription initiation at the basepair level: science.org/doi/10.1126/sc…

Seeking someone looking for a two-year postbac position to get my group up and running at Yale University! We will be utilizing chromatin tracing and other multiplexed imaging approaches to study the relationship between 3D genome organization and epigenetic memory in embryos!

(1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at Cancer Discovery! aacrjournals.org/cancerdiscover…

'caQTLs and haQTLs capture regulatory variations not associated with eQTLs and explain ∼49% of the functionally annotated GWAS loci'

Been clear for a while that accessibility & histone marks provide more info for explaining & fine mapping GWAS loci than expression. 1/

Great opportunities with exciting projects in my lab!

We are very excited today to share our work in nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)

🚨Transcription and Chromatin UK is back for 2024🚨
We will be in Newcastle from 25th to 27 Sept. Register your interest so you're the first to know when registration opens 🧬
biochemistry.org/events-and-tra…

We are looking for a PhD candidate to work on the 'histone code hypothesis' using epigenetic rewriting techniques. Deadline 12th of May.
adum.fr/as/ed/voirprop…
Romain Koszul EPIC_Unit@pasteur Gilles Fischer Maxim Greenberg Daniel Jost Geneviève Almouzni JB Boulé Leonid Mirny

Preprint alert! 🎉I am excited to share the work from our enjoyable collaboration with Wendy Bickmore Josh Brickman labs. Investigating the role of PRC2 in stabilising the developmental transcriptional response during endodermal differentiation. doi.org/10.1101/2024.0…

Do you like #ChIPseq & #CUTnRUN as much as we do?

Join the #PALSSummerSchool2024 and learn

🎨The Art of Peak Calling ⛰️
( #biochemistry and #bioinformatics )

by Anna Nordin the #CUTnRUN Master
from Linköpings universitet Wallenberg Centre For Molecular Medicine_Linköping

REGISTER > trippus.net/summerschool