tRNAs for the win!

There is still time to apply! Join my lab and find new ways to empower our immune system to fight #metastasis . We are combing wet 🧑‍🔬 and dry lab 👩🏽‍💻approaches to study the tumor-immune-axis. Find out more 👉 tinyurl.com/bdz9yv5v

As promised, the code and documentation of DeltaSplice are now available at github.com/chaolinzhangla…. Kudos to the first author Chencheng Xu! Comments/suggestions are very welcome.

The Moslehi Lab and Section of #CardioOnc & Immunology is recruiting post-doctoral candidates interested in studying the immune basis for inflammatory cardiac diseases. Email me if interested: [email protected]
UCSF Cardiology UCSF Helen Diller Family Comprehensive Cancer Ctr

Excited to share this review on one of my favorite biological problems:

Selective vulnerability in neurodegenerative disease, and how recent technologies are yielding new insights into the underlying mechanisms.

Out in Nature Rev Neurosci today!

nature.com/articles/s4158…

momi3 is here! This is an impressive extension that achieves a 1000x speedup over momi2. Very pleased to see my former PhD student, Jonathan Terhorst, thriving in his career as a PI.
doi.org/10.1101/2024.0…

Looking for a postdoc and interested in coming to NYC? Apply to NYU Biology's Emerging Scholars Symposium by April 10th! 🧑‍🎓🚀🚀🚀

Out work about 'Single Cortical Neurons as Deep Artificial Neural Networks' was finally published in Neuron

With Mickey London and Idan Segev

Neuron paper: bit.ly/3CJic8E
code: bit.ly/3CJUeKv
data: bit.ly/3xIm6uW

All new results in thread below

In a pair of bioRxiv preprints just posted w/ Sina Booeshaghi and Angel Galvez Merchan, we describe algorithms for an open data Commons Cell Atlas and demonstrate how a Human Commons Cell Atlas can be used for discovery.
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
1/🧵

Single Cell Genomics Day starts tomorrow at 10AM ET!

Come for the awesome keynotes (Jason Buenrostro , Xiaowei Zhuang, IdoAmitLab) and to learn about our favorite new methods and trends for the field in the last year. All talks streamed on Youtube and satijalab.org/scgd

What a PERFFect day to share our new preprint!

With Tsion Abay #BobStickels Meril Takizawa Ronan Chaligne (He/Him) and Ansu Satpathy, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. biorxiv.org/content/10.110… 1/n

Check out the latest from Chaolin Zhang. Solid improvement on splicing prediction tasks! No doubt DeltaSplice will be quite a powerful tool in our toolbox.

In this preprint biorxiv.org/content/10.110… with @sindri_e we compared seven widely used methods for batch correction of single cell RNA-seq data. We found that all but one of the methods introduce batch effects when there are none. 1/N