The first Cochrane Canada CAN-PCC Prevention Guideline recommendation is out:
*We suggest masking for asymptomatic adults in community settings be used for the prevention of COVID-19 infection to prevent COVID-19 condition.* (Cond Rec, Low Cert Evidence)

Minimizer score card update:

❌ It's not airborne
❌ Reinfections won't happen
❌ Kids aren't affected
❌ It doesn't transmit in schools
❌ 'Healthy, normal people' don't get long COVID
❌ Herd immunity will save us

Next up: Viral persistence is rare and inconsequential

In #LongCovid , SARS-CoV-2 persists and replicates in MKs that in turn produce platelets containing virus. Circulating spike might be an additional sign of viral persistence that could serve as a Long COVID biomarker.

The persistence of the virus could lead to abnormal platelet…

The wealthy are building “passport portfolios” — collections of second, and even third or fourth, citizenships — in case they need to flee their home country, per CNBC.

Long Covid day 465. I just left my doctor’s office, and she doesn’t think I’ll ever recover. She only has one Long Covid patient who has 100% recovered. So yeah, I guess that was my life, done at 32, lol—so much for those super mild variants. Thanks for nothing, public health.

These are biomarkers of neurological damage in diseases like MS and Alzheimers.

In this study, #LongCovid patients had higher levels of these markers than healthy controls.

nature.com/articles/s4138…

'The BA.2 omicron VOC is more aerostable than the delta VOC'

This happened because of unmitigated infections. And we're still living with unmitigated infections.

If you are enjoying your pandemic-denial lifestyle, just wait.

nature.com/articles/s4146…

JN.1 descendant KP.2 is taking off quickly, projected at 25% of US specimens. KP.2 has a few new mutations that seem to make it more fit and able to outcompete other variants. It's also evading prior immunity from vaccine and infection more than JN.1 does. biorxiv.org/content/10.110…

Salon: Can nasal Neosporin fight COVID? Surprising new research suggests it works

A potential treatment for COVID-19 may have been hiding in our medicine cabinets, a new study in PNAS has found

salon.com/2024/04/27/can…

Novavax JN.1 vaccine candidate induces neutralization responses to JN.1, JN.4, JN.1.11.1, JN.1.7, JN.1.13.1 and JN.1.16 strains... It also produces polyfunctional cellular CD4+ T cell responses to a range of omicron strains including JN.xs.

ir.novavax.com/press-releases…

About 2m people have long Covid in England and Scotland, figures show dlvr.it/T60mz9

As Co2 rises, SARS-CoV-2 is more stable and more infectious. A moderate increase from 500 - 800 increases the risk of infection. Could help explain the lack of seasonality to Covid. 😷
nature.com/articles/s4146…

Vascular Alterations following COVID-19 Infection:
A Comprehensive Literature Review

🔥Elegant overview article again underscoring that C19 is a VASCULAR DISEASE, why….read 👇and remember EVERY part of your body is blood vessel dependent, to live and survive!

➡️'COVID-19 has a

By the way, I don't know how much we can trust the 'we didn't find live virus in the milk' because these are the same people who can't seem to find live virus in the air 🤡🤡😆😭😭

A new study highlights the essential role of macrophages as the major inflammasome-activating cell population in the lungs and point to endothelial cell expressed IL-1α as a potential novel component driving the pulmonary immunothromobosis in COVID-19.

nature.com/articles/s4142…

New study. We compared the immune response of XBB and JN.1 in human infections to evaluate the necessity for #SARSCOV2 vaccine updates
Results:
JN.1 exposure induces higher neutralization against emerging mutants, including FLiRT (JN.1+346T+456L) and KP.3
biorxiv.org/content/10.110…

The story of frequent persistence of #SARSCoV2 in multiple organs after mild Covid keeps getting stronger, and correlates (odds ratio >5) with symptoms of #LongCovid
🆕The Lancet Infectious Diseases
thelancet.com/journals/lanin…

This is exactly why so many of us with long COVID stop seeking care, and why so many studies claim that when we stop seeking care we 'got better'. Bc they can't actually help us and they need us to disappear. Remember this anytime you see a minimizer saying we 'get better':

How #SARSCoV2 can disrupt brain synapses
nature.com/articles/s4156…
nature.com/articles/s4156…
Increased expression of 3 synaptic proteins, and finding a drug that restores synaptic function
Nature Microbiology

Preventing infection is the best way to avoid diseases like #PAIS . A new study from our team Tianyang Mao, Jooyoung Kim, Mario Peña-Hernández 🦇 et al shows that a generic antibiotic neomycin acts on the host immune system in the👃🏽to trigger antiviral resistance. (1/)🧵…