Image-based quantification of mitochondrial iron uptake via Mitoferrin-2 sciencedirect.com/science/articl…

(1/8) Do you eat enough choline? Have you even heard of it??

Choline is super important for the brain and must come from your diet 🐟🥚🥦

Here nature we show that FLVCR2 transports choline into the brain and use #cryoEM to show how! 🧠🔬 Filippo Mancia

nature.com/articles/s4158…

Structural and molecular basis of choline uptake into the brain by FLVCR2 nih.gov/news-events/ne…

First structures of a fungal DASS transporter! And the first DASS PO4 transporter also!

Our paper on the identification of the mitochondrial carrier involved in glycolytic intermediates transport is out! This transport step links the two halves of glycolysis, which in Stramenopiles is split between the cytosol and the mitochondrion. doi.org/10.7554/eLife.… eLife - the journal

Glad to have participated in this fantastic collaboration. An original project from Reyes Lab Institut Européen de Chimie et Biologie. Congratulations to Nico and team, and Arantza Balsebre Cajiao | Aran 👩‍🔬 from my Lab for contributing to this great article! NatureStructMolBiol #Transporters #Virus nature.com/articles/s4159…

Identification of the potassium-binding site in serotonin transporter pnas.org/doi/10.1073/pn…

Exploiting protein language models for the precise classification of ion channels and ion transporters onlinelibrary.wiley.com/doi/10.1002/pr…

Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A | Nat Commun

doi.org/10.1038/s41467…

in case you all like membrane proteins, there's a lot of cool stuff in the fresh-off the press NatureStructMolBiol issue

nature.com/nsmb/volumes/3…

Future opportunities in solute carrier structural biology nature.com/articles/s4159…

Congratulations to Simon Lichtinger and his study of the transport cycle of PepT2 with Jo Parker and Simon Newstead which just came out in eLife - the journal

doi.org/10.7554/eLife.… eLife - the journal

A lot of work!

Department of Biochemistry at Oxford University

Deorphanizing solute carriers in Saccharomyces cerevisiae for secondary uptake of xenobiotic compounds frontiersin.org/journals/micro…

Transport mechanism and pharmacology of the human GlyT1 cell.com/cell/fulltext/…

Conformational free-energy landscapes of a Na+/Ca2+ exchanger explain its alternating-access mechanism and functional specificity | PNAS pnas.org/doi/10.1073/pn…

Cryo-EM structure of the human Asc-1 transporter complex | Nat Commun

doi.org/10.1038/s41467…

Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter | Nat Commun

doi.org/10.1038/s41467…

Interested in membrane transporters? This review in the April issue from the International Transporter Consortium summarizes the current status of transporters in drug development and discusses implications for precision medicine bit.ly/4bbWwmY rdcu.be/dD7UR