They don't even know what optogenetic stimulation is!

optoKANK is a new optogenetic tool to disassemble individual focal adhesions! 🔦 In the preprint the authors find a local burst of acto-myosin contractility is necessary to disassemble FAs. The burst is caused by GEF-H1 released from microtubules.
biorxiv.org/content/10.110…

Guiding actin filaments along microchannels with optogenetic myosin: 'good motile function was achieved in one experiment, providing sufficient information [...] for sorting applications or for programming of network-based biocomputation devices'

Optogenetic control of the actin cytoskeleton in a neuroblastoma cell. Light is on when the white dot is visible. #microscopy #cell_control #science #cells_are_dynamic

My laboratory is recruiting a postdoc to work on neural population dynamics for the adaptive control of locomotion. Our approach integrates large-scale recording in freely-moving mice, EMG, behavioral and optogenetic manipulations, and computation. Feel free to get in touch!

SRO crowd at #ARVO2024 for Dr. Allen Ho's presentation featuring results from @NStherapeutics Phase 2b/3 #clinicaltrial of our MCO-010 #optogenetic #genetherapy for #retinitispigmentosa . ARVO #ophthalmology

Healing traumatic muscle injuries is a longstanding challenge in tissue engineering. Our new study in Biomaterials shows that actuating optogenetic muscle grafts with light *completely restores* functional mobility in mice within 2 weeks of injury! 🧵1/3
sciencedirect.com/science/articl…

Optogenetic Implants? Brain to Brain Interfaces? Emotion Tracking? Predictive Crime Prevention?
Only crimes I see are #CrimesAgainstHumanity & ALL the politicians are involved.
I call for a public trial in the People's Court.
Policy Horizons 2013:

horizons.service.canada.ca/en/2013/08/01/…

Now online at eLife - the journal in final form: the opus magnus by Artur Ruppel and Dennis Wörthmüller on optogenetic activation and force propagation in cell doublets. Check out the online version with its many cool animations at doi.org/10.7554/eLife.…

Happy to share that our latest study is published in Frontiers in Physiology!
We show that gradients in ventricular conduction and repolarisation can be manipulated by sub-threshold optogenetic stimulation.
You can access the paper at: doi.org/10.3389/fphys.…
Leonardo Sacconi

Check out our paper in Biosensors and Bioelectronics on wirelessly controlled, battery-free, miniature ‘flood lamps’ for optogenetic studies of the enteric nervous system and brain-gut axis in freely-behaving mice.  If you’d like access to this technology, then please let us

Audience gasps as @KapiteinLukas makes a cell run in circle with 'outcome-driven microscopy', acquisition coupled to real-time optogenetic feedback #MiFoBio2023

Extremely happy to see this review finally out “Optogenetic control of neural activity: The biophysics of microbial rhodopsins in neuroscience”, it was collaborative work with Ed Boyden doi.org/10.1017/S00335…

How can a cell lead the migration of its followers? Leone Rossetti addressed this question by generating optogenetic leaders. With them, he found a force-velocity relationship for collective cell migration. New preprint with Ricard Alert Zenón!📰 IBEC biorxiv.org/content/10.110…

Optogenetic Control of Bacterial Cell-Cell Adhesion Dynamics: Unraveling the Influence on Biofilm Architecture and Functionality

'photoswitchable adhesins between bacteria'
onlinelibrary.wiley.com/doi/10.1002/ad…

new results! We describe an optogenetic method to 'paint' patterns of morphogen signals in zebrafish embryos to guide their development. Preprint here:
biorxiv.org/content/10.110…

Check out Nathan Lord's explainer thread for the details!

Standing room only for Karl Deisseroth seminar Scripps Research. Breath of science is mind boggling: from ion channel structures, to optogenetic technologies, to understanding of the mind!

Neuroscientists wordlessly control the brain of a scampering lab mouse

With wireless optogenetic tools, neuroscientists steer mice around their cages
spectrum.ieee.org/neuroscientist…

Ccultured hippocampal dentate granule cell, expressing the optogenetic tool channelrhodopsin-YFP cell-wide (green), and immunostained for the master AIS organising molecule ankyrin-G (magenta).

Credits: Mark Evans

#MedTwitter #neuroscience