#DBfeature

Stage-specific regulation of undifferentiated spermatogonia by AKT1S1-mediated AKT-mTORC1 signaling during mouse spermatogenesis

by Lele Yang, Huayu Qi et al
sciencedirect.com/science/articl…

Mechanisms of meiosis initiation and meiotic prophase progression during spermatogenesis sciencedirect.com/science/articl…

New L-Carnitine benefit just dropped: Bigger Balls

Vitality boosting aside, L-carnitine enhances spermatogenesis. Its also a POWERFUL testicular antioxidant.

Less oxidative stress + better function = more vitality

》 Mechanism of Infertility

The exact mechanism is not fully understood, but the increased temperature from varicoceles disrupts spermatogenesis (sperm production), leading to lower sperm count, motility, and an increase in abnormal forms.

》 Treatment Options

Treatment

Tissue grafting vs SSCT to restore spermatogenesis what’s best? #16NYRA

You need to be leg extension maxing

Testicular hypoxia is one of the main detriments to spermatogenesis and leydig cells producing testosterone

You need to be producing blood flow + oxygen to your gonads by any means possible

Why?

- Enhances AR sensitivity
- Enhance test

Do environmental toxins such as (PFASs) affect human spermatogenesis?

'PFOS, PFOA, PFNA, and a mixture of PFASs decrease ROS generation in spermatogenic cells derived from hESCs.'

📕Steves AN, Turry A, Gill B, Clarkson-Townsend D, Bradner JM, Bachli I, Caudle WM, Miller GW,

A study of Magatosis reptilian spermatogenesis. Be carful who you bed.

Swallowing Sperms gives you a shining and smoothly skin …. Herrrr just get a healthy guy with a healthy spermatozoa and spermatogenesis 👌

Great talk at #UKFP24 from Christine Wyns in #Edinburgh on In Vitro Spermatogenesis

Vitamin A destroys testosterone levels:

“An excess of vitamin A leads to testicular lesions and spermatogenetic disorders, and a deficiency induces early cessation of spermatogenesis and adversely affects testosterone secretion.”

Let’s start the week by introducing Prof.Herman Tournaye, another inspiring speaker in #16NYRA ⭐️line-up!

Prof. Tournaye works at the VUB, where his research focuses on spermatogenesis and testicular stem cells. 🥜

🔗 Read our interview with Herman: nyra-youngresearch.eu/tete-a-tete-wi…

Immensely proud of Bryan Naelitz, MD & his review of red cell disorders and male infertility published in Nature Reviews Urology

In this (first-of-its-kind) review, we discuss sickle cell disease, hemochromatosis, thalassemia, etc and their effects on spermatogenesis and T

nature.com/articles/s4158…

Signatures of metabolic diseases on spermatogenesis and testicular metabolism
nature.com/articles/s4158…

Oogenesis Spermatogenesis
In Female In Males

Mengenal Spermatogenesis, Proses Pembentukan Sel Sperma pada Testis dlvr.it/T772DY

α1,4-galactosyltransferase 1 in spermatogenesis of Drosophila melanogaster: is expressed at a significantly higher level in the testis than in the ovary, regulates the sperm individualization process and maintains the survival of sperm bundles. tinyurl.com/25p47244

#glycotime

Spermatogenesis can be impaired by simply sitting — I wonder if this can explain global decrease in sperm count since we sit a lot more than our forefathers

It’s the exact opposite

Vitamin A destroys testosterone levels and causes infertility:

“An excess of vitamin A leads to testicular lesions and spermatogenetic disorders, and a deficiency induces early cessation of spermatogenesis and adversely affects testosterone secretion.”

.PacBio Iso-Seq data mapped to T2T assemblies differentiates highly similar Y chromosome ampliconic gene (YAG) families, incl. pseudogenes and protein-coding genes, which are important for understanding spermatogenesis.

biorxiv.org/content/10.110…