Trazadone… Carvedilol

Bisoprolol in patients with heart failure? This landmark trial established bisoprolol as one of 3 heart failure specific beta blockers (alongside carvedilol and metoprolol succinate), all of which with proven mortality benefit. CIBIS II Trial, Lancet 1999 ♥️

Pre workout meal.

Beef 300g => 75g Protein
Potatoes 250g => 50g carbs

Intra workout: 100mg Dextrose Monohydrate.

Pre workout drugs: Viagra 50mg & Carvedilol 12.5mg.

Be Fearless 💪🏾

Female, 42 y/o, grade 2 HTN, under treatment with Carvedilol 25mg/day and Losartan 100mg/day. Previously reported precordial and dorsal (back) pain, which were repeatedly treated as lumbalgia. Headache last night, consulting to emergency department. 220/120 mmHg. Jorge Parras

Class effect of beta blockers for heart failure? This trial showed us that unlike ACE inhibitors, beta blockers do NOT have class effect: carvedilol was superior to metoprolol tartrate in this study. COMET Trial, Lancet 2003 ♥️

44 M
Known dilated cardiomyopathy on HF meds (sacubitril/valsartan and carvedilol)
Palpitations for 3 hours.
Whats the initial rythm.? (PR > 200)
2nd ecg, post adenosine (6,12, then converted/slowed on 18)
Whats the 2nd rythm.?

Which of the following is a selective beta -1 blocker ?

A) Propranolol
B) Carvedilol
C) Metoprolol
D) Labetolol
#MedX #Drug #MedEd

#PharmaMed 💊

🔍 Which beta-blocker is preferred in patients with heart failure and chronic kidney disease?

A) Carvedilol
B) Bisoprolol
C) Metoprolol
D) Nebivolol

#MedicalQuiz #HeartFailure #BetaBlockers

'Multicenter, Prospective, Randomized Controlled Trial of High-Sensitivity Cardiac Troponin I' é o artigo do mês destacado pelo GECO. Este estudo aborda a eficácia da terapêutica combinada de carvedilol e candesartan na prevenção de cardiotoxicidade em doentes submetidos a

Select right answer use your brain .

Which selective beta blocker primarily targeting beta-1 receptors in the heart ?

A) Atenolol
B) Propranolol
C) Bisoprolol
D) Carvedilol
#MedX
#Q_Pearls

Morphology of plain (F1) (A), bile salt-enriched (F5) (B), cationic (F7) (C), and anionic (F10) (D) carvedilol-loaded niosomes by AFM. Abbreviation: AFM, atomic force microscopy.

#rcpeGIHep24
Thank you Prof Peter Hayes for rethink of Carvedilol to improve survival, no simply reducing variceal bleeding.

💊Lipophilic beta-blockers:
- propranolol, timolol, bisoprolol, carvedilol, metoprolol, and nebivolol.

💊 Hydrophilic beta-blockers:
- atenolol, esmolol, labetalol, nadolol and labetalol.

#MedEd #MedX #MedTwitter #Cardiology #CardioTwitter #CardioEd #ClinicalPearl

B Bloqueantes en hemodiálisis:
Cohorte >10mil pacientes.
📌Atenolol (>selectividad B1, <lipofílico)
⬇️☠️:general 23%, con riesgo cv 19% y sin riesgo cv 34% respecto a metoprolol
📌No diferencias en☠️ de bisoprolol, carvedilol y metoprolol
CKJ May 2024
doi.org/10.1093/ckj/sf…

💊 FDA approved beta-blockers used in HEART FAILURE !
🔸️Bisoprolol
🔸️Carvedilol
🔸️Metoprolol

✨️ Carvedilol is usually the first-choice beta blocker for heart failure.

#MedEd #MedX #MedTwitter #CardioEd #CardioTwitter #Cardiology #HeartFailure #ClinicalPearl

1ra comunicación oral de la tarde @joseignaciofortea
Carvedilol vs propanolol como profilaxis de descompensaciones🤔
En este estudio retrospectivo, los datos sugieren mejor respuesta y prevención en el grupo de Carvedilol 👌

On variceal GI bleeds 🩸 Talk by Dr. Cua #PDHWJAC2024
‼️ NSBB (preferably Carvedilol 12.5mg/day) should be considered on patients with clinically significant portal HPN to prevent decompensation 💯

I met a patient in OPD with recently diagnosed compensated cirrhosis/diabetes on 10+ medications from a gastroenterologist practicing elsewhere. I sent him back on carvedilol and anti diabetic medications.

En hemodiálisis, atenolol se asoció a ↓23% el riesgo de muerte, no fue igual para otros β-bloqueadores como bisoprolol, carvedilol y metoprolol,en ellos no se observó beneficio

Cohorte DOPPS

Hipótesis: mayor selectividad β-1 y menos dializable

CKJ 2024
doi.org/10.1093/ckj/sf…

Carvedilol Plus NUC for Patients With HBV-Compensated Cirrhosis Under Virological Suppression: A Randomized Open-Label Trial eemh.gr/carvedilol-plu…