Causes of False positive Galactomannan ELISA

A 33-year-old man with a recent hospitalization for MRSA pneumonia presents with fever. His chest x-ray is shown below. Serum galactomannan antigen is positive. Diagnosis and management?

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doi: 10.1002/fsn3.2576
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FIGURE 8

Mechanistic diagram depicting the overall interaction of Chaga mushroom components beta glycan, galactomannan, and betulinic acid with the spike protein (S‐protein) of SARS‐CoV‐2

Galactomannan ELISA

Makapuno offers plenty of opportunities for farmers, producers, and entrepreneurs. It is a source of galactomannan, which is a polysaccharide that is made up of galactose and mannose. Makapuno can also be used as a flavoring for cakes and pastries.

Image from: COCOFED

#makapuno

Performance of the galactomannan antigen detection test in the diagnosis of invasive aspergillosis in children with cancer or undergoing haemopoietic stem cell transplantation eurekamag.com/research/054/9…

Invasive fungal infection
Beta D glucan assay / galactomannan assay
Febrile The Infectious Diseases Trivia

Pap test. Vegetable material.
Can be mistaken for abnormal cells, parasites,even HSV.Is unusual findings. May be due to vaginal pessaries creams containing polysaccharide galactomannan, PMID: 16355382 #cytopath #cytofellows #pathresidents

Nice talk by Prof Florent Morio during FungiLEAD symposium in Paris about the role of galactomannan antigen in the diagnosis of fungal infection

Galactomannan from Gleditsia: A Sustainable Solution for the Food and Pharma Industries – developments from Turkmen scientists
#Turkmenistan #science

newscentralasia.net/2024/01/11/gal…

เส้นใย galactomannan จากเมล็ด Fenugreek ทำให้สูตร Resveratrol Elite ออกฤทธิ์ทางชีวภาพได้มากกว่าถึง 10 เท่า ถือว่าเป็นตัวกันแก่ที่ดีมากกก ทานประจำหน้าเด็กตลอดไปครับ ลูกรักขวดนี้เลยครับ 💙 shorturl.asia/KdJ2B

#เรสเวอราทอล #หน้าเด็ก #ลดริ้วรอย

Galactomannan can be derived from Makapuno, and it is a raw material for the production of medical gauze and hand and body lotion. It is also used for thickening, stabilizer, biodegradable or edible film, and gelling agents.

#makapuno #cset #pinoybiotek #isaaa

Always Read the Labels 'Locust' ~
Then research: Locust bean gum is a galactomannan vegetable gum. (Not a Bug)
Side effects of #Modified (Mod-erna) food starch include allergies, headaches, diarrhea, bloating, other forms of digestive distress, fatigue and more.
Soy: Gay Frogs!

The Combination of Dimorphandra gardneriana Galactomannan and Mangiferin Inhibits Herpes Simplex and Poliovirus Bentham Science

Current Pharmaceutical Biotechnology 2019; 20 (3) . Rechenchoski Z. Daniele , Samensari L. Nayara, Faccin-Galhardi C. Ligia , de Almeida R. Raimundo

Histoplasmosis (Histoplasma conidia): From bird or bat droppings in soil, infection thru inhalation when soil disturbed; High inoculation & immunosuppressed at risk for severe/disseminated dz.; Dx: Pos+ enzyme immunoassay of galactomannan antigen (cell wall), serum antibodies

📢📰Published in Pediatric Blood & Cancer, chest CTs & abdomen/pelvis CTs provide clinically relevant information during the prolonged febrile neutropenia evaluation, whereas BDG, galactomannan, BAL, & sinus CTs have less certain utility.
UTSW Pediatric HemOnc Pediatric Oncol

Histoplasmosis (Histoplasma conidia): From bird or bat droppings in soil, infection thru inhalation when soil disturbed; High inoculation & immunosuppressed at risk for severe/disseminated dz.; Dx: Pos+ enzyme immunoassay of galactomannan antigen (cell wall), serum antibodies

Galactomannan is vital for diagnosis of aspergillosis, but is it helpful during treatment?

In Open Forum Infectious Diseases by TID🌟Daniel Friedman🏳️‍🌈, repeat BAL GM did NOT correlate w/ outcomes. Paschalis Vergidis MD Raymund Razonable Mayo Clinic Infectious Diseases

Added by Dilek Ince Carver College of Medicine to Asper📁
transplantid.net/EVJNBL9R

Histoplasma galactomannan also X-reactive with food. Histoplasma antigen detection in unconfirmed pulmonary tuberculosis and cross‐reactivity with Aspergillus antigen in patients and in food in Jakarta, Indonesia - Mycoses - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.111…

Galactomannan inhibits Trichinella spiralis invasion of intestinal epithelium cells and enhances antibody-dependent cellular cytotoxicity related killing of larvae by driving macrophage polarization doi.org/10.1051/parasi…