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Metabolic waste: Your body's cells produce waste products that are normally excreted or broken down and reused. In a leaky gut, these waste products can get into the bloodstream more easily.

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The gut microbiota is capable of producing neurotransmitters such as serotonin, which is most well known for regulating mood and behavior. Serotonin also regulates gut motility, which is essential for proper digestion and absorption. The gut microbiota can produce serotonin by…

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Microbes: The gut contains many different types of bacteria, some beneficial and some potentially harmful. In a leaky gut, bacteria and other microbes (like yeasts or viruses) can potentially cross the intestinal barrier and enter the bloodstream.

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Macrophages are a type of immune cell that are responsible for engulfing and destroying foreign substances, such as bacteria and viruses. They are also involved in the regulation of inflammation and the initiation of tissue repair.

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Leaky gut, or increased intestinal permeability, is when the lining of the small intestine becomes damaged, causing undigested food particles, toxic waste products, and bacteria to 'leak' through the intestines and into the bloodstream. Thread Time....

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Toxins: These are harmful substances that are usually kept out of the bloodstream and excreted in the feces. They can come from the diet or be produced by bacteria in the gut.

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Zonulin: This is a protein that regulates the permeability of the junctions between the cells in the wall of the digestive tract. It's believed to be a biomarker of increased intestinal permeability.

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Undigested food particles: Normally food in your gut is broken down into its smallest components—amino acids from proteins, fatty acids from fats, and simple sugars from carbohydrates. If your gut is leaky, larger, undigested food particles can pass through into your bloodstream

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In a healthy gut, the cells that make up the mucosal barrier in your intestines are packed closely together, controlling what gets through and into the rest of your body. This is called 'selective permeability,' meaning only certain substances can pass through.

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The gut-brain axis consists of the central nervous system (CNS), autonomic nervous system (ANS), hypothalamic-adrenal-pituitary (HPA) axis, and the gastrointestinal tract’s innervation, also known as the enteric nervous system. Neural and hormonal communication pathways allow the…

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In a 'leaky gut,' the tight junctions between the intestinal cells become damage, allowing substances that normally wouldn't pass through to enter the bloodstream. These can include:

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Larger molecules: These can include anything from proteins to cells or parts of cells that would normally be kept out of the bloodstream.

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Numerous nutrients found in nature can bolster your overall health. Observations of the few remaining cultures adhering to a Paleolithic-style diet reveal improved health, leaner physiques, and longer lifespans compared to those consuming diets laden with sugar, grains, seed…

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