1/🧵Fusion of Neurons in COVID
🔹At 2 yrs many #LongCOVID pts still suffer 🧠
🔹We’re beginning to understand why
🔹“Fusogens” activated by viruses like COVID can create irreversible cell-to-cell damage & miscommunication
Pic = Spike infected neuron
Link in Tw 3
Neuronal communications facilitated by SNARE proteins with which synaptic vesicles fuse to the plasma membrane and release the neurotransmitter.
By Ryu, J.K et al.
#neuroscience
Stunning live imaging of neuronal networks in awake mice. - Ca2+ activity of 16,000 cortical neurons.
Source: Alain Chédotal
#neuroscience
Super exciting talk by Andreas Trumpp HI-STEM - Cancer and Stem Cells in Heidelberg #EACR2023 . Massive neuronal sprouting into solid tumors contributes to aggressive tumor growth and targeting these 'tumor-associated neurons' might open new therapeutic avenues 🤯 Adds neurons among crucial regulators of the TME.