The accomplishments and legacy of Saul Hertz, MD: ow.ly/ryG750QUon9

#NuclearMedicine #ThyroidCancer #Theranostics Michael Hofman

The prevalence of low TBS was about one-third in patients with HD. Female sex was the only associated factor for low TBS (OR 5.88, p <0.001). The role of TBS for fracture risk prediction needed further study. #hemodialysis #osteoporosis #TBS #CKD

The PROMISE V2 used for clinical trial updated the PSMA expression score for PSMA therapy. Lesions with PSMA uptake >liver (>spleen for PSMA-1007) defined as positive. For more details: sciencedirect.com/science/articl… #psma #prostatecancer #petct

The proposed RAI activity for DTC patients with low risk (>2 cm) and intermediate risk was 2.2-3.7 GBq (50-100 mCi) with rhTSH, tends to be lower than the past #i131 #thyroid #nuclearmed #eanm #snmmi #radioiodine

Late DMSA scan had almost 100% sensitivity and NPV for detecting high-grade VUR (grade III-V). Further VCUG may not be needed if there is normal late DMSA scan. For more details: pubmed.ncbi.nlm.nih.gov/30859438/ #VUR #pediatrics #infection #DMSA #renalscar

The recent SNMMI/ EANM Guideline for estrogen receptor imaging mentioned causes of false-positive FES PET such as physiologic uptake at uterus, ovary, and pituitary gland, post-RT lung fibrosis, etc. For more details: jnm.snmjournals.org/content/65/2/2… #breastcancer

NM imagings for diagnosis of OM. Three-phase BS or F-18 FDG PET/CT for peripheral OM. Ga-67 or F-18 FDG PET/CT for spinal infection. WBC scan +bone marrow scan for DM foot and periprosthetic OM. #osteomyelitis #petct #infection #bone

Calculation and interpretation of GBEF for diagnosis of GB dyskinesia (functional GB disease) based on CCK and fatty meal. Low GBEF means poor GB contraction and can predict post-cholecystectomy symptomatic relief. #gallbladder #disidascan #GBEF

How long is the turnaround time for the bone scan report in your clinical practice?

E-consults may reduce untimely phone call and “curbside consultation” that interrupt the radiologist’s workflow. For more details about design and implement of E-consult Service at pubs.rsna.org/doi/10.1148/rg… #radiologist #consultation #radiographics

Recently published article in efficacy and safety of Ac-225 PSMA therapy in mCRPC. For more details: thelancet.com/journals/lanon… #psma #psma therapy #prostatecancer #ac225

The real-world treatment patterns and clinical outcomes of Lenvatinib in 308 RAI-R DTC patients. The median PFS was 49.0 mo. For more details: link.springer.com/article/10.100…

Guidelines for using ERNA (MUGA) for measurement of LVEF in patients with anthracycline therapy. For more details: pubmed.ncbi.nlm.nih.gov/36334105/ #lvef #cardiotoxicity #heart #mugascan #eanm

#NewProfilePic Happy New Year 2024 #updateinnm

From the SNMMI/ EANM 2023 Guidelines, Ga-68 imaging could be 10-20% underestimation in small lesions (10-15 mm) compared with Cu-64 due to its higher positron energy. Another main advantage of Cu-64 is its longer T1/2. For more details: jnm.snmjournals.org/content/64/2/2…

PROMISE V2: There are 2 currents criteria for response assessment using PSMA-PET, PPP (PD and non-PD) and RECIP (PD, PR, CR, SD). For more details: clinicalkey.com/#!/content/pla…

2023 ESC Guidelines:
1. F-18 FDG PET/CT is recommended in possible PVE to detect valvular lesions and confirm IE.
2. Intense focal or heterogeneous uptake should be considered a major criterion for PVE.
3. A time interval prior to PET is questionable***
#esc

Tc-99m Mebrofebin HBS has an important role for assessment of future remnant liver function (FRLF) prior liver surgery. Patients with FRLF >2.70%/min/m2 had high NPV for liver failure after the surgery. For more details at pubmed.ncbi.nlm.nih.gov/30386047/ #liver

The fetal thyroid develops follicle and colloid production at 10-12 wk of gestation. Inadvertent radioiodine therapy after the 10th-wk gestation can cause fetal and neonatal hypothyroidism. #i131 #pregnancy #fetus #gestation

Do you always do a pregnancy test prior to radioiodine treatment in patients with hyperthyroidism and thyroid cancer?