Ashwin Varma(@varma_ashwin97) 's Twitter Profileg
Ashwin Varma

@varma_ashwin97

Currently: MD Student @UTHealthSA Former: Associate @BCG, Clinical Trials @MDAndersonNews, External R&D @Celgene, Summer Associate, @Lux_Capital. Views my own.

ID:797601576

calendar_today02-09-2012 05:48:10

5,9K Tweets

1,8K Followers

5,0K Following

Ashwin Varma(@varma_ashwin97) 's Twitter Profile Photo

Despite being explained this in detail by Keith Hornberger , I still cannot believe this is orally bioavailable. Beyond the Rule of Five indeed.

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Ashwin Varma(@varma_ashwin97) 's Twitter Profile Photo

There is a lot of follow-on drug development, largely triggered by the increase in PoS from a first in class agent! We should think about how to regulate these follow on efforts to maximize social benefit!

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Ingo Hartung(@HartungIngo) 's Twitter Profile Photo

Holy shit! Revolution Medicines’ G12D inhibitor RMC-9805 covalently labels the oncogenic aspartate with a aziridine warhead making use of 9 (!) stereocenters to achieve potency, selectivity & stability. My thoughts & prayers are with the process chemistry team.

Holy shit! Revolution Medicines’ #KRas G12D inhibitor RMC-9805 covalently labels the oncogenic aspartate with a aziridine warhead making use of 9 (!) stereocenters to achieve potency, selectivity & stability. My thoughts & prayers are with the process chemistry team. #AACR24
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