Venk Murthy MD PhD
@venkmurthy
#cardiometabolic #prevention; Multimodality #cvimaging; Posts may be my opinions & are not medical advice; RT≠endorse
ID:25029854
https://scholar.google.com/citations?user=nNET6osAAAAJ 18-03-2009 04:47:46
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Today in the The Lancet, we UK geneticists argue: 'Population screening requires robust evidence—genomics is no exception'
Anneke Lucassen, Helen Firth, Bill Newman, Caroline Wright, Margaret McCartney, @wilkie_lab, Robin Lachmann,TomlinsonGroup,Lucy Raymond authors.elsevier.com/a/1iD4W_3CjG8W…
PRS was hyped precisely as a stand alone screening test!
When Cecile Janssens Frank Harrell & I pointed out that CAD PRS was at best moderate effect size, people attacked us personally & suggested we had ill motivations, were luddites, or fools
Few in the genetics community pulled…