Linking up individual sugar molecules is notoriously hard, which is why enzymes make cyclodextrins, used in skincare products and drugs. It has been impossible to make their mirror-image forms, until now... Story be me, thanks to Fraser Stoddart @yongwu1990 Sophie Beeren

In case you missed it:

'Quantitative determination of the binding capabilities of individual large-ring cyclodextrins in complex mixtures' by Sophie Beeren and first author Dennis Larsen.

Sophie Beeren

pubs.rsc.org/en/content/art…

Now online:

News & Views on the Article by Yong Wu Fraser Stoddart & co-authors at Northwestern Chemistry HKU Chemistry

nature.com/articles/s4416… ($)

Synthesis of L-cyclodextrins by Sophie Beeren

nature.com/articles/s4416… ($)

For those who are into the history of chemical compounds here is a summary of a few of synthesis-related milestones for cyclodextrins produced by Yong Wu. The University of Hong Kong Northwestern Northwestern Chemistry The University of Texas at Arlington

Come and join my team! PhD and Postdoc positions available. We are looking for organic and supramolecular chemists to explore new ways of using enzymes for chemical synthesis of carbohydrates.
efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…

Come and join my lab! I am looking for a PhD student and postdoc to work on my ERC project ENZYME-DCC. We are combining supramolecular chemistry with enzymology to synthesise oligosaccharides. efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…

I'm looking for two post-docs with expertise in supramolecular and synthetic organic chemistry to join our group working on enzyme-mediated dynamic combinatorial chemistry. You can read about the positions here: dtu.dk/english/about/…

Our collaboration with Ivan Aprahamian got a write-up in Chemistry World too!

Our paper together with Ivan Aprahamian in
Chem (bit.ly/3cZVRZ9) written about in a Dutch Newspaper!
nrc.nl/nieuws/2021/06…

In collab with Sophie Beeren we show Chem the use of a photoremovable hydrazone template in the enzymatic synthesis of g-CD, thus eliminating the energy consuming steam distillation process used in industry that drastically increases g-CD production costs bit.ly/3cZVRZ9

Put a ring on it! I spoke with Ivan Aprahamian and Sophie Beeren about their work on a cheaper, light-powered gamma-cyclodextrin synthesis (in C&EN (Chemical & Engineering News)): cen.acs.org/synthesis/Taki…

Just out in Chem! Photoswitch control of g-CD production!!! Great collaboration between Ivan Aprahamian and Sophie Beeren, proud to have been part of it.

My latest publication was mentioned in C&EN (Chemical & Engineering News)! So cool. Great collaboration between Ivan Aprahamian and Sophie Beeren. cen.acs.org/synthesis/Taki…

Two PhD Scholarships and one Post-Doctoral Position available in Supramolecular Chemistry from September 2020. Sophie Beeren DTU Chemistry DTU

At pH 5 or pH 9? In 50 % ethanol or 7.5 M salt solution? Warm or cold? Bring it on! #CGTase is truly 'the little enzyme that could' …mistry-europe.onlinelibrary.wiley.com/doi/abs/10.100… #SysChem #SRBgroup #templatedirectedsynthesisofcyclodextrins Sophie Beeren Kemi på DTU

Reaching for the sun - Dynamic combinatorial chemistry with carbohydrates #syschemposter

Take a look at our latest cover art for 'Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system' by Sophie R. Beeren et al. DTU!

Find the full paper here: ow.ly/rFfo50xE3si

Molecule of the year...I am biased towards the antiaromatic nanocage (last choice): cen.acs.org/synthesis/CENs…

this week...anti-aromatics: nature.com/articles/s4158…