Lisa Kelly, BASIL Research Nurse at Solihull Research Showcase – celebrating BASIL trials for International Trials Day!

CReST showed that stenting as a bridge to surgery reduces stoma formation without detrimental effects in colon cancer patients with left-sided colonic obstruction #ICTD2023 BJS tinyurl.com/2p9uh8s8

Recruiting from 80 hospitals in 7 global south countries, CHEETAH RCT found that 1 in 8 surgical site infections could be prevented by changing gloves and instruments before fascial closure for abdominal surgery The Lancet NIHR Global Surgery #ICTD2023 tinyurl.com/4p32e4p3

The STOP-ACEi Trial showed that in people with advanced and progressive chronic kidney disease, discontinuation of RAS inhibitors was not associated with difference in rate of decrease in kidney function measured using eGFR NEJM #ICTD2023 tinyurl.com/42whfnwd

Jointly delivered with Birmingham Cancer Research UK Clinical Trials Unit the MSc in Clinical Trials provides a foundation to clinical trials covering theoretical & practical aspects of the design, conduct, analysis and interpretation of trials. Developed for a broad audience from industry, NHS Trusts & academia #ICTD2023

Published in Journal of Clinical Oncology, FOxTROT showed that six weeks of preoperative chemotherapy for operable colon cancer can be delivered safely and provides better 2-year disease control #ICTD2023

tinyurl.com/4mmmm5sj

Funded by Gates Foundation, the E-MOTIVE Trial cluster randomised trial showed an immense 60% reduction in severe postpartum haemorrhage after vaginal delivery, reducing the risk of haemorrhage-related maternal death NEJM #ICTD2023 tinyurl.com/ydn86mbz

BCTU, a UKCRC registered trials unit was 25 years old in 2022. Clinical Trial Units play a key role in the design and delivery of clinical trials. To celebrate #ClinicalTrialsDay we will be tweeting about some of the trials we have delivered over the past 12 months.

Proud beyond words of the work of colleagues from Uni of Birmingham
Medical and Dental Research (UoB) IMSR Institute of Applied Health Research Partnering with the World Health Organization (WHO) and Gates Foundation , implementation of the intervention would have huge impact .

If anyone is interested to know more about FOxTROT, Jenny Seligmann's tweetorial is essential Friday lunchtime reading!

🥁🥁🥁Tweetorial
FOxTROT, the 1st ph 3 RCT of neoadjuvant chemo (NAC) in locally advanced colon cancer
We report that NAC is
✅deliverable and safe
✅led to statistically significant reduction in cancer recurrence than upfront surgery
A 🧵 (1/14)
#crcsm
ascopubs.org/doi/full/10.12…

Lots of questions emerging about #obstructionrisk in foxtrot-study #NAC group❓

We've done a deep dive into this in upcoming #analysis (available Q2 2023) BASO~The Association for Cancer Surgery RSM Coloproctology Section 🔬

A (short) thread 🧵

Young BJS Young ESCP European Society of Coloproctology @ACPGBI Julio Mayol Jenny Seligmann
(1/X)

📢 News: FOxTROT, a trial we funded, has shown that starting chemotherapy before surgery, instead of after, can significantly cut the risk of colon cancer coming back. The findings could change how doctors treat colon cancer in the NHS and around the world bit.ly/3iUSRnd

Thank you to The Guardian Guardian Healthcare for featuring the FOxTROT trial results in today's publication!
theguardian.com/society/2023/j…

Our trials WILL, iHOLDS, Giant PANDA and CAPE are all being exhibited at the BCTU stand at #BMFMS at Birmingham's Millennium Point today. Come and speak to the teams for more information on these exciting trials #clinicaltrials #WomensHealth