Blood Advances
@BloodAdvances
Blood Advances, a digital open-access journal from the American Society of Hematology, @ASH_hematology
ID:732570175162179585
http://www.bloodadvances.org 17-05-2016 13:55:15
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Real-world applicability of the International Metabolic Prognostic Index in DLBCL: a validation cohort study
ow.ly/E9WX50Rmr2b #lymphoidneoplasia
Maintenance therapy for early loss of B-cell aplasia after anti-CD19 CAR T-cell therapy
ow.ly/bq3m50RmqWc #immunobiologyandimmunotherapy #lymphoidneoplasia
Haploidentical bone marrow transplantation for AML in remission after TBF conditioning: a long-term follow-up
ow.ly/jHSN50RmqRl #clincialtrialsandobservations #myeloidneplasia #transplantation
Peripheral blood regulatory T cells associate with teclistamab failure, whereas CD8+ effector T cells associate with teclistamab response. ow.ly/hogy50RbM1J #lymphoidneoplasia #immunobiologyandimmunotherapy
IPI risk factors are associated with different genetic and tumor microenvironmental signatures in DLBCL. ow.ly/aLwS50RbM5C #lymphoidneoplasia
Gene-corrected RAG2 locus restores V(D)J recombination in stem cells of patients with RAG2-SCID, promoting TCR and B-cell receptor formation. ow.ly/KL1k50RbLXW #genetherapy #hematopoiesisandstemcells
We present a novel immunotherapy platform for hematological cancers that exploits fundamental metabolic dysregulation of cancer cells. ow.ly/e6ro50RbLTK #immunobiologyandimmunotherapy #myeloidneoplasia
There is a strong correlation between the stage and severity of granulocyte development disruption and the efficacy of G-CSF therapy. ow.ly/TYop50RbLJ7 #phagocytesgranulocytesandmyelopoiesis
Our multivalent, thiol-reactive chemistry covalently links immune adjuvants to free thiols on cancer cell debris induced by chemotherapy. ow.ly/cfwv50RbMrW #immunobiologyandimmunotherapy #myeloidneoplasia
We propose a new classification of VWD type 2M/2A for p.R1315L, p.R1374H, and p.R1374C because they share a common phenotype with 2M and 2A. ow.ly/Ebqs50RbMIU #thrombosisandhemostasis #vascularbiology
RBC transfusion can restore quiescence in previously activated immune cells under inflammatory conditions, such as sickle cell disease. ow.ly/V8Ac50RbLFu #transfusionmedicine #redcellsironanderythropoiesis #vascularbiology
Among individuals at elevated risk of multiple myeloma, obesity is positively associated with mass spectrometry–detected MGUS. ow.ly/TOPe50RbM0m #lymphoidneoplasia
Different forms of congenital neutropenia exhibit disruptions in granulocyte development at distinct stages. ow.ly/buMP50RbMyb #phagocytesgranulocytesandmyelopoiesis
Understanding differences in RBC survival may inform hemoglobin composition thresholds required to reverse the phenotype after gene therapy. ow.ly/sUzh50RbLtT #clinicaltrialsandobservations #genetherapy #redcellsironanderythropoiesis #transplantation
A similar proportion of participants remained on antibiotics at 12 months as those on immunoglobulins, with similar rates of major infection. #clinicaltrialsandobservations #lymphoidneoplasia
Human hematopoietic stem cells can be corrected to restore endogenous RAG2 gene expression while preserving durable engraftment potential. ow.ly/hGtG50RbMeT #genetherapy #hematopoiesisandstemcells
AML with myelodysplasia-related genetics can be combined as a single group encompassing MR-defining gene mutations and cytogenetics. ow.ly/IJVx50RbKgI #myeloidneoplasia #healthservicesandoutcomes
Monosomy 7 and del(7q) result in a 1-copy deletion of the NAMPT gene at 7q22.3. ow.ly/zszR50RbHFl #myeloidneoplasia