Sangyun Lee accardilab Boudker Lab Robertson Laboratory @ WUSTL reveal the mechanism by which protons gate a CLC-type Cl-/H+ exchanger

nature.com/articles/s4159…

An exciting time in Solute Carrier research. Here are some of the areas where SLC structural biology is heading and where future opportunities for new discoveries and therapeutic interventions await. rdcu.be/dE759 nature.com/articles/s4159… Department of Biochemistry at Oxford University Kavli Institute for Nanoscience Discovery, Oxford

Thrilled to announce our latest work in NatureStructMolBiol on HS-AFM single-molecule structural biology with Scheuring Lab ! Marching towards our long-standing goal, we've directly linked the conformations of a single molecule to its instantaneous activity... nature.com/articles/s4159…

Read about the next chapter in our fruitful collaboration with Scheuring Lab! New HS-AFM developments help visualize the conformational landscapes of individual glutamate transporters, leading to many cool insights about their mechanism. Congrats to Yining Jiang and all authors!

The Blanchard lab is looking to hire a leader. This posting is for a Scientist position at St. Jude Children's Research Hospital in the Department of Structural Biology, Memphis, Tennessee. Review job details and apply today! talent.stjude.org/careers/jobs/J…

Nature research paper: Ion and lipid orchestration of secondary active transport go.nature.com/3OXW4is

The Biophysical Society folks made a slick flyer you can share. (It's a PNG) #womeninSTEM

Transporter aficionados unite! In nature, Olga Boudker and David Drew provide a comprehensive review of how secondary active transporters can couple substrate transport to ion gradients, and how lipids can regulate transport mechanisms.

nature.com/articles/s4158…

We loved having you around!

Cheers to a great #BPS2024 , and our yearly tradition of lab dinner (with friends)! Here's the aftermath of our triumphant victory over all-you-can-eat hotpot 🦞

Olga Boudker Prof Renae Ryan Krishna Reddy Paul Riegelhaupt

Plenty of chances to talk about transporters, evolution, and allostery with me at #BPS2024 - come say hi! 👇🏾

A beautiful collaboration with
accardilab Robertson Laboratory @ WUSTL is out! Using a battery of structural/biophysical techniques, we show that CLC-ec1 undergoes large-scale, pH-dependent structural changes - we propose this underlies common gating. Read below!

nature.com/articles/s4159…

I am recruiting PhD students Princeton Computer Science interested in ML applications in bio!

Our group aims to define new problems for AI in molecular & structural bio. We work at the intersection of many areas incl 3D vision & generative modeling for proteins. Plus we make useful tools!❄️🐉

Ion channels are synthesized in pairs! Go figure! pnas.org/doi/epdf/10.10…
Congrats to the great team effort on this one!