I had the pleasure of moderating a discussion between Drs. Colleen Bond and Andy Webb regarding use of nicardipine versus clevidipine in the neuro patient! On Neurocritical Care Society podcast series: podcasts.apple.com/us/podcast/neu…

Pharmacotherapy debates times! 🥊🥊

Up first: should nimodipine be continued when patients are on pressors for vasospasm?

Megan Barra, PharmD says yes

Antiplatelet Use and Ischemic #Stroke Risk in Minor Stroke or Transient Ischemic Attack: A Post Hoc Analysis of the POINT Trial bit.ly/3AKcEZy Shadi Yaghi Brian Mac Grory Clay Johnston Mohammad Anadani

Military study showing significant mortality reduction with ROTEM-guided resus compared to std of care in univariate, multivariate, AND propensity-matched models

Everyone should have TEG/ROTEM in the trauma bays at this point

bit.ly/3dylqy4

Intravenous valproate, levetiracetam, and fosphenytoin stopped status epilepticus that was resistant to initial treatment with lorazepam in approximately half the patients and did not differ significantly in effectiveness. nej.md/2OFitRQ

May be reasonable to choose tenecteplase over IV alteplase

Initiation of a fixed-dose four-factor prothrombin complex concentrate protocol | Our latest research using 1500 units for all indications link.springer.com/article/10.100…

Josh Goldstein MGH Emergency Med

#Naloxone administered intranasally may not be as effective as intramuscular injections for reversing #opioid overdoses. JAMA Network Open

Ready for flu season 🤧 in your Emergency Dept? Review the 2018 IDSA guideline update on season influenza with this helpful infographic by Kelly (Wong) Heidepriem, MD

aliem.com/2019/11/guidel… IDSA

From Pages to Practice: Dabigatran Anticoagulation to Reduce Stroke Recurrence nej.md/2JRtoH3 via NEJM Resident 360

Prospective evaluation of 4F-PCC for reversal of factor Xa inhibitors #critPRN
bit.ly/2X5A8o9

In a review of hazardous chemical emergencies & poisonings, the authors explain the effects of exposure to respiratory irritants, vesicants, asphyxiants (including cyanide), and cholinergic agents (organophosphate insecticides and military nerve agents). nej.md/2ISppcZ

Yes. Yes. Can I even draw up 312.5 mg?

Also check out Sergey Motov's awesome #Opioid Algorithm!

It’s finally happened. Hot off the press!

The release of ConSEPT and EcLiPSE in The Lancet

Which is the best 2nd line treatment for children in status epilepticus?

Phenytoin v levetiracetam

Team DFTB got a sneak preview to bring you our analysis

dontforgetthebubbles.com/consept-eclips…

Guidelines Review: Infographic by Kelly (Wong) Heidepriem, MD summarizing the 2018 ACEP Guideline Update on ED Procedural Sedation with PROPOFOL covering such issues as:

- Pediatric vs adult bolus dosing
- Coadministration with ketamine/fentanyl
- NPO status

aliem.com/2019/04/guidel…

Should we add muscle relaxants to ibuprofen for acute low back pain? jwat.ch/2Pe7EWN AnnalsofEM

We receive almost daily reminders of the fragility and temporality of human life, and yet continue to delude ourselves that we’ll ‘take some time off next year’ or ‘go travelling one day’ or ‘work long hours now to save for retirement’.

Wake up. Live your life. TODAY.

Free! NEJM Knowledge+ Pain Management & Opioids focus module – earn mandated pain management CME and learn evidence-based strategies for assessing and managing pain. #meded #painmanagement #opioids Sign up today kpl.us/pain-opioids