Combining eight #omics technologies, KI researchers have developed a web-based platform for researchers worldwide that provides a whole new insight into the human body at the cellular level. Published in Genome Biology. #multiomics #SingleCell Atlas news.ki.se/advanced-cell-…

Prof Ebba Sohlberg NK cell expert Karolinska Institutet GREAT TALK! Educates on adaptive NK cells/restricted by a single KIR/returns to “missing self” hypothesis/HLA-C mismatch unleashes killing/Developed GMP alloreactive ADAPT-NK #TIMO2024 Society for Immunotherapy of Cancer HLA-E checkpoint conversion

In this article, we provide a brief perspective of the promise of allogeneic cell therapies against cancer. We consider rejection by the recipient as a central pitfall and discuss approaches to reduce this rejection by genetic engineering

nature.com/articles/s4157…

In this Perspective in Nature Rev Immunol, we discuss strategies to confer cell-intrinsic, immune-evasive properties to allogeneic T cells and NK cells in order to prevent or delay their immune rejection Precision Immunotherapy Alliance, UiO - Det medisinske fakultet Oslounivsykehus Center for Infectious Medicine rdcu.be/dFBAM

New paper from us: shorturl.at/fgHQ1 in Science Immunology where we explore regulation of immune system diversity in endometrium and identify compartment-specific (blood vs endometrium) environmental factors contributing to variation Karolinska Institutet Center for Infectious Medicine #nkcells

Fantastic talk by Renato Ostuni on cancer microenvironment & IL1b+ macrophages!… Cell identify and niche identity 😍

Karolinska Institutet Seminar by KISS & Center for Infectious Medicine

Happy International Women's Day!

We're celebrating women who have changed the world. Here's all of the amazing women who have received the #NobelPrize and their remarkable achievements at the time of the award.

Who are the women who inspire you the most?

#IWD2024

New pre-print from us online at bioRxiv we make use of human uterus and bone marrow transplantation to determine functional characteristics of uterine immune system replenishment #nkcells #tcells #tissueimmunology tinyurl.com/mrx7u4pu

How does a monocyte become a macrophage?

We found intestinal stromal cells guide macrophage differentiation via
GM-CSF in human gut!
Now out Nature Communications Karolinska Institutet
rdcu.be/dzE7J

Have you registered for the EMBO Tissue Resident Immune Cells in Health and Disease, 20-23 March 2024, Marseille, France. meetings.embo.org/event/24-immun…

The abstract deadline has been extended to 15th  Feb, slots still available for short talks. So get applying!

Congratulations to post doc Chris Stamper for his first author paper about single cell sequencing of fresh and frozen tonsils!! Also thank you to all our collaborators at Sophiahemmet and everyone else involved in the paper!

Thrilled to share our collective report on a novel classification of human peripheral blood Natural Killer cells. An effort from the MetaNK consortium, a group of 20 laboratories worldwide, intended to serve as a reference point for NK cell research.
researchsquare.com/article/rs-387…

Don't miss out! Exciting Mucosal Immunology conference #ICMI2024 in Copenhagen.
Abstract deadline is 31 January.
socmucimm.org/meetings-event…

T cells keep it on! Excellent work on T cell immunity against the new SARS-CoV-2 variant BA.2.86 from Karolinska Institutet around the team of Marcus Buggert.

Looking forward to our next #globalimmuno talk this Wednesday, January 10th at 9am PST, noon EST, 4pm GMT by Dr. Michal Schwartz.

Title: “The immune system protects the healthy mind”
LINK: ucsd.zoom.us/j/91053505061

Are you a #postdoc interested in #immunology and how our immune system reacts to #enterovirus infection and #vaccination ? Want to help find a prevention for #T1D ? This could be an opportunity for you: ki.varbi.com/what:job/jobID… #postdoc jobs FlodströmTullbergLab Center for Infectious Medicine Karolinska Institutet

It's hard for MAIT cells to move on from severe COVID-19! Have a look into our study now out at J Immunol showing the aftermath on the human blood MAIT cell compartment long after recovery from disease.
🧵1/5

journals.aai.org/jimmunol/artic…

Happy to share new work from us on persisting impairment of #MAIT cells in people recovering after very severe #COVID19 . These results suggest weakened antimicrobial #immunity in this patient group.
journals.aai.org/jimmunol/artic…
Karolinska Institutet Center for Infectious Medicine J Immunol

Sekine group is recruiting for curious minds! 🧬🧫🧪🔬Please apply or spread the word 🗣️
ki.varbi.com/what:job/jobID…

Hurra! 🎉  Vi är så glada att vi nu kan satsa 120 miljoner på klinisk forskning. 10 projekt inom tex immunterapi, kirurgiska metoder, skräddarsydd läkemedelsbehandling och stöd för återhämtning kan nu starta studier där behandlingar testas på patienter.
cancerfonden.se/nyhet/extra-sa…