And that's a wrap! Thank you for joining us today for 'Unlocking Complex Cell-based Gene Therapies.'

Watch the full meeting here: youtube.com/watch?v=-QJXlB…

#CGT

Fantastic afternoon Friends of Cancer Research Parker Institute for Cancer Immunotherapy #CRT session moderated by Mackall Lab, with Dr Marcela Maus providing nuanced insights into the assessment of cell-based therapies (given their heterogeneous nature) and a diverse panel discussing clinical evaluation of these therapies

“Thinking back to it now, given the option I would have totally taken the risk with cell therapies from the get-go if I had known about it.” Chris White reflecting on his experience and the potential of cell-based gene therapies during 'Session 2.

youtube.com/watch?v=-QJXlB…

An absolutely amazing talk by Dr Marcela Maus Systematically laying out a path for improving patient care. Intentional heterogeneity to select for cell therapy enhancements where in matters, in vivo. Harvard Medical School Mass General Brigham

Our 2nd panel discussion is underway as PICI Center Director Stanford University Crystal Mackall (@MackallLab), MD, guides conversation on immunotherapy treatments w/ PICI Investigators Phil Greenberg, MD, (@fredhutch), @marcelamaus, MD, PhD, U.S. FDA experts & patient advocates.

A MUST watch event through Parker Institute for Cancer Immunotherapy and Friends of Cancer Research on 'Unlocking Complex Cell-Based Gene Therapies'. A few slides/comments shown by Dr Marcela Maus that are important to reiterate on recent studies of possible secondary T cell malignancies from lenti/gene edited products.

To kick off our afternoon, Dr Marcela Maus shares approaches for incorporating multiple gene edits into cells for cell therapy. #FriendsCGT

Starting now! Session 2: Discovering & Developing the Next Generation of Cell-based Gene Therapies: Considerations for First-in-Human Trials.

youtube.com/watch?v=-QJXlB…
#CGT Parker Institute for Cancer Immunotherapy Friends of Cancer Research

Dr Marcela Maus Discussing how to incorporate more safety thru #productdesign #protocoldesign #characterization #releasecriteria to innovate #firstinhuman #clinicaltrial . #cancer #celltherapy #cgt Parker Institute for Cancer Immunotherapy Friends of Cancer Research FDA Biologics FDA Oncology

“I knew there were risks with my treatment, but I wanted to see my children grow up, so I took that risk,” said patient advocate Desiree A.H. Walker, on her experience as a patient during this important discussion at our #CGT workshop w/ Friends of Cancer Research on cellular therapy development.

Unlocking Complex Cell-based Gene Therapies Session 2 is starting now! “Shaping the Future of Cell and Gene Therapies: Challenges & Opportunities.”

Watch live:  youtube.com/watch?v=-QJXlB…
#CGT

How do you balance safety, innovation, regulation, access a panel of #patientadvocates #academia #fda to discuss how we can #worktogether to advance medicine. Parker Institute for Cancer Immunotherapy Friends of Cancer Research FDA Oncology

After fantastic talks by Carl June and @Marsonlab about the current state of CAR therapies, Toni Ribas is leading a great panel about balancing the need to advance cellular therapy development with patients’ need for access to safe therapies Friends of Cancer Research Parker Institute for Cancer Immunotherapy

“We need to understand the limitations of these models. They are each going to have their advantages and disadvantages. This needs to be considered when interpreting the data.” Iwen Wu, CBER, U.S. FDA discussing gene editing live during session 1.

youtube.com/watch?v=-QJXlB…
#CGT

“I knew there were risks with my treatment, but I wanted to see my children grow up, so I took that risk.” Patient advocate Desiree Walker speaking live at Friends & Parker's #CGT meeting about her experience as a #patient .

youtube.com/watch?v=-QJXlB…

#CGT

The first panel at Friends of Cancer Research and Parker Institute for Cancer Immunotherapy’s focuses on challenges and opportunities for shaping the future of cell and gene therapies. #FriendsCGT

Starting now! Panel 1 Discussion and Q&A

Shaping the Future of Cell and Gene Therapies: Challenges & Opportunities

youtube.com/watch?v=-QJXlB…

Very exciting to learn about CRISPR editing that can delete genes that interfere w/effectiveness of CAR-T to make the CAR-T more effective. Technology being developed at Gladstone Institutes and elsewhere.

Alex Marson, from Gladstone Institutes is presenting live on 'Opportunities to Enhance Adoptive T Cell Therapies using CRISPR Gene Editing.'

Join us here: youtube.com/watch?v=-QJXlB…

Alex Marson discussing how #clinicaltrials can both advance a #livingdrug but also through competitive #cart persistence can guide future #cart #innovation #cgt Friends of Cancer Research Parker Institute for Cancer Immunotherapy