Systematic analysis of proteome turnover in an organoid model of pancreatic cancer by dSILO dlvr.it/T63z93

Proud to see our paper describing BARtab and bartools, two integrated software tools for the analysis of synthetic cellular barcodes is now published Cell Reports Methods! We hope the community finds this work useful.
cell.com/cell-reports-m…

Bioengineering has captured our attention due to its impact in solving real-world problems and its potential to lead to new biological insights. Visit our joint collection for #bioengineering content across the Cell Press portfolio: hubs.li/Q02tK60Q0

Analysis of synthetic cellular barcodes in the genome and transcriptome with BARtab and bartools dlvr.it/T61M5K

Excited about our recent paper in Cell Reports Methods on LC-MS/MS based global O-glycoproteome analysis in blood plasma co-led by Taewook Kang and Rohit Budhraja from our team #teammassspec #glycotime Cell Reports Methods Taewook Rohit budhraja

Roy Walker, Patrick Cai and myself put together a commentary on the methodological advances enabled by the Sc2.0. We hope it's a valuable condensed read for the synthetic biology and synthetic genomics community. Now online in Cell Reports Methods.

cell.com/cell-reports-m…

Cell Reports Methods and Cell Reports have collaborated on a joint special issue on #bioengineering . You can read the papers here: hubs.li/Q02r_Wcm0

High-fidelity Cas9 variants that prevent off-target cleavage typically reduce on-target activity. Adding TurboCas9 mutations to these enzymes can improve activity while maintaining off-target fidelity. Cell Reports Methods
cell.com/cell-reports-m…

We have optimized a human in-vitro translation system (HITS) for use in #ribosome research

Our HITS:
🧪requires a minimal number of components
💵is cheap & easy to prepare
💡enables cap-dependent translation
📈is highly active

online now: bit.ly/49xTdVa
Cell Reports Methods

Directed-evolution approach to empower EGFR targeting for immunotherapy dlvr.it/T5d5Js

Combining LIANA and Tensor-cell2cell to decipher cell-cell communication across multiple samples dlvr.it/T5bpNs

A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation dlvr.it/T5bTmW

Nextflow pipeline for Visium and H&E data from patient-derived xenograft samples dlvr.it/T5XzcB

Haplotype-resolved assembly of diploid and polyploid genomes using quantum computing dlvr.it/T5RHq7

Enhancing comparative T cell receptor repertoire analysis in small biological samples through pooling homologous cell samples from multiple mice dlvr.it/T5R0lQ

Mutational rescue of the activity of high-fidelity Cas9 enzymes dlvr.it/T5NxQL

A highly optimized human in vitro translation system dlvr.it/T5Ncw2

An autologous ex vivo model for exploring patient-specific responses to viro-immunotherapy in glioblastoma - a study by Erasmus MC martine lamfers, Eftychia Stavrakaki & others in Cell Reports Methods #AACR24 hubs.li/Q02rxfPF0

Online now! An engineering strategy to target activated EGFR with CAR T cells
Read the full article by BOKU University Michael W. Traxlmayr et al. in Cell Reports Methods #AACR24 hubs.li/Q02rwTDZ0

Global O-glycoproteome enrichment and analysis enabled by a combinatorial enzymatic workflow dlvr.it/T57B4V