β-Amyloid is a cytokine (kinocidin-type); where kinocidins are immunopeptides with the properties of both cytokines and antimicrobial peptides. What are the implications for drug design for AD?
β-Amyloid Is a Kinocidin Cytokine | ACS Chemical Neuroscience pubs.acs.org/doi/10.1021/ac…

See: scientificamerican.com/custom-media/d…
An important commentary on the ballooning economic cost of dementia and the need for better resourced research on neurodegeneration. We can pay now or we can pay more later!

Research is our only path to a better tomorrow. Words we must remember, especially within the context of humankind's struggle to conquer neurodegenerative disease.

Endogenous Antimicrobial-Immunomodulatory Molecules: Networking Biomolecules of Innate Immunity pubmed.ncbi.nlm.nih.gov/38658319/

Beta-Amyloid is part of a synergistic self-triggering network of antimicrobial-immunomodulatory molecules - perhaps a useful insight for drug design!

Chemists Invent Drugs and Drugs Save Lives - Weaver - ChemMedChem - Wiley Online Library …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cm…

Medicinal chemistry/drug design is indeed a crucial element in the health and socioeconomic well-being of humankind.

So many illnesses affecting humankind; we need to be passionate about drug design and drug discovery

This recent review article from Donald Weaver on druggable targets for the immunopathy of Alzheimer's disease is now available to read, go take a look👀👇

pubs.rsc.org/en/content/art…

📍 University Health Network Chemistry at UofT University of Toronto

#DYK there are things you can do to improve your brain health?

In Episode 10 of Krembil Brain Institute's #YourComplexBrain podcast, learn about the top 5 science-based tips to keeping your brain fit & healthy at any age - featuring University Health Network experts!

Listen & subscribe! bit.ly/3ytUf4p

It's always a pleasure to speak with Dr.SaskiaSivananthan about the way forward in Alzheimer's research, as we both have the same goal - to help patients.

If this topic is of interest, consider giving this episode a listen.

I am honoured and grateful to receive this Krembil Chair in Drug Discovery in Alzheimer's Research, and fellowship award, which will help us to continue our work and train many new scientists. Thank you to everyone who attended today's event.

Global pharmaceutical company Takeda will exclusively license small molecules that target tau, which were developed by Treventis, building on the Alzheimer’s & neurodegenerative research expertise of Donald Weaver's lab at University Health Network.

Read more: bit.ly/3UuBJTz

How does #stress rewire our brain? And is stress contagious? These fascinating questions + more are answered in Episode 1 of our #YourComplexBrain #podcast featuring Dr. Jaideep Bains, with Dr. Kathryn Curtis & @FarrahSchwartz. 👏👏👏

Listen & subscribe! bit.ly/3ytUf4p

I was referred a patient with 'dementia' only to discover that she was malnourished; she recovered completely with an improved diet. Her city had become a food desert and she suffered for it.

Read here: bit.ly/41XHQ66

Thank you The Peoples Pharmacy for featuring my research. I enjoyed speaking with you.

People living with dementia may have difficulties recognizing cold or dangerous weather conditions. With a winter storm coming, it's important to check in on your loved ones.

In today's Media Digest: Krembil Brain Institute researchers identify new model of #Alzheimers as an autoimmune disease

Krembil Brain Institute University Health Network
uhn.ca/corporate/News…

This is a proud yet bittersweet post, as it is my last Krembil Annual Report launch as Director.

It has truly been an honour.

In this report, you will learn how our team is working hard to improve lives through research and care >> bit.ly/3LWOmTk

September is #WorldAlzheimersMonth . The annual cost of dementia to the Canadian economy & healthcare system is >$10.4 billion. This devastating diagnosis for patients will also have a devastating economic impact. It is critical that we invest in neurodegenerative research.

NEW essay in The Conversation Canada by @drdonweaver: ' #Alzheimer ’s might not be primarily a brain disease. A new theory suggests it may be an autoimmune condition.'

Read it here: theconversation.com/ca & watch the video below, to learn more. ⬇️

University Health Network University Health Network_Research Alzheimer Society of Canada Krembil Foundation