As we near 550 participants in the multi-omic precision medicine study IBD-RESPONSE, thanks to BMJ_Open for publishing our protocol - patient pathway and analytical plans for microbiome, single cell transcriptome, genetics, metabolome and diet - bmjopen.bmj.com/content/14/4/e…🦠🍏🧬 🙏

PANTS - Maximising patient data and samples + fantastic collaboration

Recruitment March 2013- July 2016

PANTS - FACTS
👥 1600+ patients
🩺13900 patient visits
🏥118 NHS Hospitals
👩‍💻300 NHS research staff
🧪~90000 frozen samples
💩~6000 poo samples
Tariq Ahmad

New research - Chanchlani et al - Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn’s disease: 3-year data from the prospective, multicentre PANTS cohort study

thelancet.com/journals/langa…

#GITwitter #IBD

Seb The Lancet Gastroenterology & Hepatology Nick Kennedy Tariq Ahmad BSG Trainees BSG Research Anjan Dhar

Delighted to see 🇬🇧 PANTS study 3 year extension data published in The Lancet Gastroenterology & Hepatology
🙏🏼 to the investigators and patients who participated
sciencedirect.com/science/articl…

⏺️Only 1/3 of those treated with TNFis remain in remission at 3years
⏺️Week 14 levels significant in reducing…

📣 💥
Opportunity to be the next #IBD fellow to join our team at IBDHull to horne your skills in complex #IBD management and develop research 🔬🧐 skills

Friendly integrated clinical and research #IBD team
👇
DMs open. Please retweet 🙏🏼

jobs.nhs.uk/candidate/joba…

I’ve been working with the British Society for Immunology (BSI) to develop a new online training course on IBD immunology in clinical practice.

The first gastroenterology day is on 5th June;
details 👉bit.ly/3x2jEEV
BSI Congress & Events JimBrewer Nikolas Plevris Beatriz Gros

📢📢 People living with Crohn's or colitis in the UK & diagnosed in the last 5 years, please consider joining one of our 90 min focus groups this April. We would love to hear your thoughts on our new research plans to study gut microbes and the immune system. For more info 👇 🙏

Pharmacogenomics! Cool study design! Important results! Chris' study has it all. Another important Exeter IBD contribution #ECCO24 #ECCO2024

Clear presentation at #ECCO24 by Chris Roberts on our reverse phenotyping analysis of NUDT15 in the NIHR IBD BioResource 💙 cohort
ExeterIBDresearch Tariq Ahmad

Early drug treatment leads to better outcomes for Crohn’s disease, via New Scientist

newscientist.com/article/241851… #ECCO2024 #ECCO24 #GITwitter #IBD

Amazing talk from James Lee at #ECCO24 on the work his lab have done related to ETS2 in #IBD and its potential for therapeutic advances

Preprint on Biorxiv:
biorxiv.org/content/10.110…

PROFILE: biomarker-stratified comparison of top-down vs accelerated step up tx for newly diagnosed Crohn’s

❌no biomarker–treatment interaction

✅Sustained steroid and surgery-free remission sig more frequent w/ top-down vs accelerated step-up

#GITwitter #ECCO2024 #ECCO24

Are you part of a clinical team helping to look after patients living with IBD? 👥

Then this is the survey for you! 🌟

The annual ECCO survey looking at a treat-to-target approach to IBD is now live 🎯 #ECCO24

Please complete and share widely 🌍

survey.ecco-ibd.eu/index.php/surv…

Thank you Nick Kennedy NickPowellLab BSG Research BSG for organising in the beutiful Exeter

Good luck to all for the great line-up of talks & speakers at the BSG IBD Clinical Research Group meeting 👥🌟✅

From our team:

Dr Nuru Noor will be presenting on the PROFILE Trial PROFILE Crohn's Trial

Prof Miles Parkes will be presenting on the UK IBD BioResource NIHR IBD BioResource 💙

What does editors looks for ? . Helpful tips from Rob Brierley #EIC of The Lancet Gastroenterology & Hepatology

Thank you Ron for attending the BSG Research #IBD investigators meeting