GLP-1 is the 2023 Breakthrough of the year Science Magazine. Wonderful to see the health benefits for people living with obesity/diabetes. Will be exciting to see if GLP-1 helps combat obesity-associated cancer risk, one of the questions in our COMBAT team proposal Cancer Grand Challenges

So, my daughter got a puppy today! Then says 'Sorry to overshadow your day Mom'
Congrats to BOTH Dori and Kimryn Rathmell

Online now! Metabolic modulation of mitochondrial mass during CD4+ T cell activation by Kiran Kurmi, Marcia Haigis, and colleagues at Harvard Medical School University of Rochester Medical Center #chembiol dlvr.it/Sw8Vyz

Excited to share our recent findings on how formate, in combination with anti-PD-1 therapy, enhances CD8+ T cell fitness in the tumor microenvironment Marcia Haigis, Jared Rowe, Arlene Sharpe

Truly honored to receive The Beug Foundation Prize for Metastasis research! beugstiftung-metastase.de

Formate Supplementation Enhances Anti-Tumor CD8+ #TCell Fitness and Efficacy of PD-1 Blockade, by Jared Rowe, Ilaria Elia, Marcia Haigis, Arlene Sharpe et al.
bit.ly/3FaGDyb
Dana-Farber Harvard Medical School #Immunotherapy

Some examples of what institutes can do ⏬

In Lausanne, we have campus #daycare , holiday #camps for older kids, #technician support during maternity leave, #independence transition grants, etc etc

Yes, the demand often exceeds the availability, but real efforts are being made..

I am very honor to be selected as 2023 Lubin Scholars from the Dana Farber Cancer Institute. It’s the first transitional grant I received. I am extremely grateful for the generous financial support from the Lubin Family Foundation for the next four years!!

Congratulations to the newly minted Dr. Bing Shui on his paper describing the global regulation of miRNA function by oncogenic K-Ras. Another piece of the puzzle.
cell.com/molecular-cell…

REVIEW | Led by Jae Bum Kim (Seoul Nat Univ):

The authors discuss the regulation of #lipogenesis , the physiological & pathological role of lipogenesis in adipose tissue, liver, neurons & cancer, & how lipogenesis may be targeted therapeutically.

nature.com/articles/s4225…

I also want to congratulate the other awardees and thank the Ho-Am Foundation for putting on such amazing award ceremony show. hoamfoundation.org/eng/award/this…

An honor to receive the Samsung Ho-Am Prize in Medicine in Korea last week. Special to share this celebration with Kevin Haigis Lab and family! This would not be possible without the incredible teamwork of @haigislab and collaborators. Thank you Samsung Electronics and Ho-Am Foundation.

It is with great sadness that we announce the passing of our colleague, mentor and friend Professor Fred Goldberg, a pioneer in the study of the proteasome & protein degradation.

Today we report Cell Metabolism on a new Resource called FALCON, super proud of co-first authors Juli Coraor Fried and Nicolas Wieder and grateful for all collaborators!
cell.com/cell-metabolis…
Broad Institute Mass General Brigham Innovation Brigham and Women’s Research Harvard Medical School The Harvard/MIT MD-PhD Program HST

Dr. Jennifer Guerriero (Jennifer Guerriero, PhD) Brigham and Women’s Department of Surgery is studying the regulation of tumor-associated macrophages and immune cell metabolism with PARP inhibition ( #PARPi ) in #breastcancer . guerrierolab.bwh.harvard.edu #WomenInScience #BCSM