📑 Altered profiles of circulating cytokines in chronic liver diseases (NAFLD/HCC): Impact of the PNPLA3I148M risk allele

journals.lww.com/hepcomm/fullte…

📑 Do pts w cirrhosis +/- MHE have longer reaction times (RT) in a newly developed virtual reality driving test⁉️

Prospective Study:
👉Pts w MHE had longer RTs compared to no MHE or controls
👉Longer RT asscoiated w ⬆️ car accidents/🛑 driving due to HE

journals.lww.com/hepcomm/fullte…

📑 Serum 25-hydroxyvitamin D, type 2 diabetes, and liver-related outcomes❗️

☀️Synergistic association of vitamin D deficiency and T2DM with liver-related outcomes
☀️Vitamin D deficiency associated with ⬆️ liver-related outcomes in individuals with T2DM

journals.lww.com/hepcomm/fullte…

📑 Mortality causes in patients with cirrhosis❓
 
In this study including, >200,000 patients from 2000-2017 , Peter Wang et al found:
 
⭐️ Compensated or #NAFLD  ➡️ 🫀disease and non-liver cancers 
⭐️ Decompensated or #ALD  ➡️ liver causes
#LiverX

journals.lww.com/hepcomm/fullte…

Everything you need to know about complementary and alternative medicine and the liver

Massive review from TheLiverDoc in Hepatology Communications

Open access journals.lww.com/hepcomm/fullte… #livertwitter

📑 #NAFLD and NAFLD liver-related deaths are 📈 globally and across all ages‼️

🌏 East and South Asia as well as Middle East and North Africa are experiencing the largest increases in NAFLD

journals.lww.com/hepcomm/fullte…

Thanks for highlighting!
Let us all work to ⬆️ use of brief alcohol interventions in routine clinical care!

Great teamwork: Jonathan Melendez Wei Zhang MD PHD Ahmad Anouti, MD Amit G Singal Thomas G. Cotter, MD MS et al!

There is no safe amount of alcohol in cirrhosis

Even “non-alcoholic” cirrhosis

But most people drink every week

many never receive any guidance or intervention from their doctor

Let’s change that

Author: Jeremy Louissaint
In: Hepatology Communications
journals.lww.com/hepcomm/fullte…

‼️ Mobile apps are powerful tools to monitor symptoms and engage in treatment for patients with liver disease

✅ Our editorial with Elliot Tapper summarizes the mobile apps in liver disease and offers suggestions for the path forward Hepatology Communications

journals.lww.com/hepcomm/fullte…

I am biased

Sure

But Hepatology Communications is publishing great reviews, supporting rising stars, and getting super lucky to catch amazing trials, novel ideas, and important qualitative studies journals.lww.com/hepcomm/pages/…

Excited every time I look at the latest articles page

Genetics of liver disease

Phenomenal review covering everything you need to know about the role of genetics in diseases common and rare and whom to sequence / test

Open access journals.lww.com/hepcomm/fullte…

#livertwitter

Grateful to Silvia Vilarinho and co authors Konkwo and Chowdhury for this great paper in Hepatology Communications

journals.lww.com/hepcomm/fullte…

They did it!

A natural language processing algorithm to pull out all the features of liver biopsy reports

journals.lww.com/hepcomm/fullte…

#livertwitter

📑 Outcomes following liver transplant for #alcohol -associated liver disease!

🔵 Survival is excellent!
🔴 But, return to 🍺🍷🥃 higher
🔮 Tools used to predict return to harmful drinking perform poorly
#LiverTwitter #GITwitter #OpenAccess

journals.lww.com/hepcomm/Fullte…

📑 Women #hepatologists report #bias against pregnancy 🤰🏻and barriers to childrearing 👩🏽‍🍼including limited parental leave

#EndBias #Equity #Advocacy

journals.lww.com/hepcomm/fullte…

We hear a lot about 'leaky gut' in cirrhosis, but which gut segment is leaky and are certain bacteria 🧫 associated with leaky gut⁉️
 
Duodenum is the leakiest segment in cirrhosis, and certain bacteria are associated with leaky gut❕
  #LiverTwitter

journals.lww.com/hepcomm/fullte…

Clinical criteria miss moderate alcohol-associated hepatitis

Is there a role for biopsy? And what should the criteria be?

From Dr Nipun Verma in Hepatology Communications

journals.lww.com/hepcomm/fullte…

They developed a way to use CRISPR to treat liver cancer

Future so bright #livertwitter

Open access journals.lww.com/hepcomm/fullte…

Hepatology Communications

At Hepatology Communications we published a study that used Mendelian randomization to examine the impact of a gene on bilirubin levels and debunk multiple spurious associations

That gene literally controls bilirubin metabolism!

journals.lww.com/hepcomm/fullte…

📑 Evaluating the predictive performance of the elderly patient calculator #TIPS score in a North American cohort

🔹Overall ExPeCT score had highest discrimination for post-TIPS ☠️   
🔹ExPeCT scores were suboptimally calibrated in the cohort 
#LiverX

journals.lww.com/hepcomm/fullte…