Thrilled to share our article in nature showing that FOXO1 overexpression enhances CAR T cell persistence & metabolic fitness in treating solid cancers. Huge effort from Jack Chan Christina Scheffler Isabelle Munoz, & co-led by A/Prof Paul Beavis, myself, & DarcyLab!
rdcu.be/dEmg8
Hey we published in nature (woah)
The story: #FOXO1 + CAR-T = a good combo (wow)
It's back-to-back with the esteemed Evan Weber + Mackall Lab (huge)
Work by Christina Scheffler Isabelle Munoz Junyun Lai @paulbeavis + Phil (big CAR-T energy)
nature.com/articles/s4158…
Isabelle Munoz Isabelle Munoz is a postdoc in A/Prof Paul Beavis lab developing CART immunotherapies using CRISPR-Cas9 technology. She previously worked on understanding mast cell degranulation in allergy Institut Imagine, and the role of epigenetic factors in hematopoiesis @Institutcochin
Jack Chan nature Evan Weber Mackall Lab Christina Scheffler Isabelle Munoz Junyun Lai Paul Beavis Congratulations Jack and all of the co-authors!
Junyun Lai nature Jack Chan Christina Scheffler Isabelle Munoz A/Prof Paul Beavis Woo!!! Congratulations Jun!!!!
Jack Chan nature Evan Weber Mackall Lab Christina Scheffler Isabelle Munoz Junyun Lai Paul Beavis Congratulations!!! So cool to see the final version, your work is just beautiful.
