What are the cardiovascular disease associations and genetic determinants of epicardial and pericardial adiposity?

ja.ma/4bho9tS

In both primary and secondary prevention populations, higher lipoprotein(a) was associated with increased cardiovascular risk independent and regardless of high sensitivity CRP level. ja.ma/43VfMSd

Today the JAMA Cardiology Editorial Board met to discuss plans for the journal, which is dedicated to publishing research on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy.

Most viewed in the last 7 days from JAMA Cardiology:

What is the optimal antiplatelet regimen in patients with ACS undergoing PCI who are at both high bleeding and ischemic risks?

ja.ma/3UDJ0lW

Children and adolescents in higher fitness quantiles exhibited lower cumulative incidences of anxiety disorders, depressive disorders, and ADHD, finds nationwide cohort study encompassing 1.9 million participants in Taiwan. ja.ma/3WeSDsl

Findings suggest that a deep learning-based neural network improves detection of congenital long QT syndrome (LQTS), including concealed LQTS, and can distinguish between the 2 most common genetic subtypes. ja.ma/43PxtTv

Study findings suggest that race and gender are significantly associated with the probability of donor heart acceptance and that investigation is needed to change modifiable factors contributing to these disparities. ja.ma/3JCEhKB

Most viewed in the last 7 days from JAMA Cardiology:

What is the optimal antiplatelet regimen in patients with ACS undergoing PCI who are at both high bleeding and ischemic risks?

ja.ma/44k38wj

Most viewed in the last 7 days from JAMA Cardiology:

Does plozasiran, an investigational APOC3-targeted small interfering–RNA therapeutic, safely and effectively reduce serum triglyceride level in patients with severe hypertriglyceridemia?

ja.ma/3JpT3o6

This Viewpoint discusses the impact of sinus node dysfunction and escape junctional rhythm associated with the Fontan procedure on patient outcomes. ja.ma/3UgxbAE

Analysis shows that initial declines in HF-related mortality from 1999 to 2012 have been entirely undone by subsequent reversals from 2012 to 2021, meaning that contemporary HF mortality rates are higher than in 1999. ja.ma/3UcwM23

Viewpoint examines whether overdiagnosis rather than underdiagnosis may now be the dominant form of myocardial infarction misdiagnosis. ja.ma/3UbxJb2

Catheter ablation for AF was associated with reduced risk of HF events in patients with HFrEF but had limited or no benefit in HFpEF. ja.ma/44lr82o PHRI.ca Population Health Research Institute 🇨🇦

Individuals with persistent favorable sleep patterns over 5 years had a lower CVD risk, even among those with higher genetic risk. These findings highlight the importance of maintaining favorable sleep patterns over time for CVD prevention. ja.ma/3QgR0q7

Cardiopulmonary exercise testing may be useful in characterizing distinct patterns of functional impairment across the spectrum of amyloid infiltration and predicting outcomes in patients with transthyretin amyloidosis. ja.ma/3xstArw

A novel aortic stenosis polygenic risk score (PRS) performed comparably to most clinical risk factors in risk estimation of aortic stenosis. However, the addition of a PRS to clinical risk factors had only incremental improvement in risk estimation. ja.ma/3PWgol2

Case report: a diagnosis of Leriche syndrome in a male patient with peripheral arterial disease, erectile dysfunction, and nonischemic cardiomyopathy. ja.ma/3vVMh6p

JAMA Medical News Director jenabbasi and Douglas Drachman discuss late-breaking research from #ACC24 and World Congress of Cardiology. Hosted on @amaedhub. ja.ma/3W4m6oE American College of Cardiology

Most viewed in the last 7 days from JAMA Cardiology:

Does plozasiran, an investigational APOC3-targeted small interfering–RNA therapeutic, safely and effectively reduce serum triglyceride level in patients with severe hypertriglyceridemia?

ja.ma/3W576XI

Most viewed in the last 7 days from JAMA Cardiology:

Is antibiotic prophylaxis associated with decreased risk of infective endocarditis after invasive dental procedures?

ja.ma/4aR5xR8