The Mouse N-Glycome Atlas - High-resolution N-glycan analysis of 23 mouse tissues. biorxiv.org/cgi/content/sh… #bioRxiv

Searching for a universal, bottom-up proteomics method? Max Perutz Labs Vienna performed a comparative survey of the 16 most common methods to provide a basis for selection preparation strategies in MS proteomics. pubs.acs.org/doi/10.1021/ac…

#glycotime
As abnormally glycosylated glycoproteins are specific to tumor cells, they offer unique targets for CAR T therapy!
Excellent review on CAR T cells for solid tumors by Zoe Raglow,Mary Kathryn McKenna,Malcolm K. Brenner,David M. Markovitz &others.
bit.ly/3KrkVry

Pleased to share our Science Translational Medicine paper uncovering old drugs which target #BH4 ( #tetrahydrobiopterin ) metabolic pathway and explore their new roles in #chronicpain .
> science.org/doi/full/10.11…
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This might be interesting for CAR T cell researchers-
colleagues have developed a stabilized, monomeric version of CD19 (termed 'superfolder') which will potentially be a very useful tool in diagnostics and studying CAR biology.
pubs.acs.org/doi/10.1021/ac…

🧑🔬🦠🔬 An interdisciplinary research team involving #BOKU solves the 'sugar brake' and develops highly effective SARS-CoV-2 receptor mock-up. Chris Oostenbrink Johannes Stadlmann
➡️ Read more: short.boku.ac.at/ez2e8g0
➡️ To the paper: dx.doi.org/10.7554/eLife.…

🧑‍🔬🦠🔬 Ein interdisziplinäres Forschungsteam unter Beteiligung der #BOKU löst die 'Zuckerbremse' und entwickelt hochwirksame SARS-CoV-2 Rezeptor-Attrappe. Chris Oostenbrink Johannes Stadlmann
➡️ Mehr dazu: short.boku.ac.at/ez2e8g0
➡️ Zum Paper: dx.doi.org/10.7554/eLife.…

Removing the N-glycans of hACE2 increases its binding strength to Spike and makes it a better SARS-CoV-2 interceptor: doi.org/10.7554/eLife.…
Grand collaboration between 朴 正義 ☮️ Bascule Inc 🌏 KIBO宇宙放送局, Chris Oostenbrink, BioToP PhD School, PenningerLab, IMBA, University of British Columbia, APEIRON Biologics AG, Med Uni Graz, Karolinska Institutet

Its been an amazing lab course on Protein Characterization 朴 正義 ☮️ Bascule Inc 🌏 KIBO宇宙放送局. Estimating protein copy-numbers per cell using SRM on a refurbished QQQ (BIG thanks to @vbcf_tweets!!!). Fearless students, great spirit and DIY attitude. Much appreciated!

Ctortecka et al.'s data establish a novel and reproducible approach to markedly expand the numbers of proteins one detects from ultra-low input samples — BOKU University IMBA Vienna BioCenter Claudia Ctortecka MendjanLab

mcponline.org/article/S1535-…