Wrapping up a great first session with José Luis Ricon José Luis Ricón Fernández de la Puente, and Dr's Karim Mekhail Karim Mekhail , Kyle Loh, and Jeff Wrana Wrana Lab
Went to MaRS Discovery District for the first a week ago & met with Dr Karim Mekhail, a strong longevity supporter. Super excited to hear about his forthcoming research - watch this space! Karim Mekhail University of Toronto @marsdd
Researchers from the University of Toronto, led by Drs Karim Mekhail & Razqallah Hakem, have discovered how the nuclear envelope, which surrounds the nucleus, is involved with the repair of DNA double strand breaks, a severe form damage to DNA when both strands are completely cut. 1/4
Join us at the Genomic Instability and DNA repair Keystone meeting this March in Whistler! Doudna Lab Agnel Sfeir Xiaolan Zhao Lab Gaëlle Legube lab Chromatin Repair altmeyerlab Karim Mekhail hopfnerlab Roger Greenberg andre nussenzweig lab Daniel Durocher Helle Ulrich Fabrizio d'Adda di Fagagna Karlene Cimprich
Courtney Hudson-Paz Time Initiative Session 1 introduced aging biology + focused foundational studies on the mechanisms of aging and stem cell biology, featuring José Luis Ricón Fernández de la Puente (@RetroBio_ ), Dr Karim Mekhail (@UofT_LMP ), Dr. Kyle Loh (@StanfordMed ), and Dr Wrana Lab (@SinaiHealth)
For the fourth anniversary of COVID-19 being declared a pandemic by the World Health Organization (WHO), we spoke to Dr. Talya Yerlici, (postdoctoral fellow, Dr. Karim Mekhail's lab) about her contributions as first author to a paper published in Cell Reports:
🔗lmp.utoronto.ca/news/researche…
Karim Mekhail Princess Margaret Cancer Centre Research Department of Laboratory Medicine & Pathobiology Medical Biophysics NUS @histiocytosisX Sinai Health Philipp Maass The Hospital for Sick Children (SickKids) Absolutely a pleasure to have contributed to this exciting work!
Identifying dsbNETs (DSB-capturing nuclear envelope tubules) and their regulators as key factors promoting faithful DNA damage repair and cell survival
biorxiv.org/content/10.110…
#dnarepair #dsbNETs
Study from the lab of Dr. Karim Mekhail, “DNA double-strand break-capturing nuclear envelope tubules drive DNA repair”, published in NatureStructMolBiol, will fundamentally change how we look at DNA repair. 🧬
Watch the interview: ow.ly/O7r050RhzPv
Story: ow.ly/TZby50RhzPw
Really Cool Paper from Karim Mekhail and collaborators!
DNA double-strand break–capturing nuclear envelope tubules (dsbNETs) drive DNA repair
nature.com/articles/s4159…
Unveiling human DNA repair process🧬
A study led by Dr. Razq Hakem University Health Network and Dr. Karim Mekhail Temerty Medicine uncovered that human cells use nuclear envelope tubules to repair DNA, a process evident in several cancer types.
doi.org/10.1038/s41594…;
temertymedicine.utoronto.ca/news/toronto-r…
Karim Mekhail Cell Reports Dr. Talya Yerlici Congratulations Karim, Talya, and the team! 🎉
Thank you to our collaborators Dr. Brian Raught and Dr. Razq Hakem and the rest of the team!
Karim Mekhail Department of Laboratory Medicine & Pathobiology Temerty Medicine
