Congratulations to MacMillan Group postdoc Steve Knutson for being awarded a K99/R00 NIH NIGMS Pathway to Independence Award to develop new proximity labeling tools for RNA biology!

Well done, Steve!

Online now! #Review Current advances in photocatalytic proximity labeling by Steve Knutson, David W.C. MacMillan MacMillan Group, and colleagues at Princeton Chemistry @Princeton dlvr.it/T5yB46 #chembiol

“People are suggesting scientists are elitist. This is exactly the opposite of what science is. Scientists are doing everything for the community. They are not sitting at the top of the mountain they are sitting at the bottom trying to make sure everyone can get to the top of the…

17 years in the making..

We are super excited to finally achieve alcohol-alcohol cross-coupling enabled by the powerful SH2 radical sorting! Great work Jerry, Nick, Jay, James, Colin and Robert. Big shout out to our collaborator Jesus from Janssen Spain.

science.org/doi/full/10.11…

A light-driven reaction sequence that bolts nonaromatic rings onto heteroarenes, such as pyridines, offers a rapid route to medicinal molecules that would be troublesome to make using existing methods: cen.acs.org/synthesis/Phot…

Check out our recent paper where we take diols and bromoalcohols to form strained bicyclic, fused, and spirocyclic compounds through a new concept, couple-close. Big thanks to our collaborators at Janssen Pharmaceuticals at Spring House!

nature.com/articles/s4158…

🔬 Celebrating the brilliance of women in the MacMillan lab this #InternationalWomensDay ! Our female scientists inspire excellence every day. 💪🧪 #WomenInSTEM #ChemistryWonders #IWD2024

Check out our work on alkene dialkylation by sorting not one, not two, but THREE radicals! Great work Johnny and Will!
nature.com/articles/s4158…

Congratulations to the MacMillan Group on their paper out today in nature: “Alkene dialkylation by triple radical sorting.”

Well done Johnny, Will, and Dave!

Story here: bit.ly/49vA4n6

Interested in converting an aliphatic alcohol directly into its bioisostere? Check out our method for deoxydifluoromethylation of alcohols. Congrats to Edna, Nico Cesar Nicolas, and Holt Sakai! Read the full paper out now in J. Am. Chem. Soc..

pubs.acs.org/doi/10.1021/ja…

Annual MacMillan Lab Secret Santa Party #HappyHolidays #GiftedChemists

For more awesome SH2 work, check out this pre-print by the Baran Lab and Shenvi Lab, who leverage SH2 using an iron porphyrin complex for RAE/olefin cross coupling. We hope many others with join the SH2 movement and explore all it has to offer!

chemrxiv.org/engage/chemrxi…

SH2 shines again! Check out this pre-print by our lab, where we leverage SH2 to couple abundant alcohols and olefins. Great work Anna, Iona, Nate, and Amy!

The photoreactors have finally arrived in China, and we are thrilled to start conducting photoredox chemistry MacMillan Group with them.

Happy Thanksgiving from all of us at the MacMillan Lab! 🍁🦃

chemrxiv.org/engage/chemrxi…

Check out this preprint on the sorting of three distinct radicals for alkyne dialkylation! Awesome work from Johnny and Will.

Thank you, David, for this amazing lecture
It’s an honor that you become fellow of our academy
A person committed to science and life, wellcome! MacMillan Group

Today in Madrid, following a speech on his #Nobel Prize-winning chemistry, David MacMillan of MacMillan Group will be inducted into the Spanish Royal Academy of Sciences.

Congratulations Dave! #chemistry

Excited to share a photo from recent visit of our phenomenal former MCWhite group undergrads Will Lyon and Andria Pace who are rock star grad students in MacMillan Group

Researchers at Princeton Chemistry's MacMillan Group have unlocked a pathway to using earth-abundant metal photocatalysts with a discovery that exploits an unusual phenomenon called the Marcus inverted region: bit.ly/3FoUBwE