CardioNerds Journal Club This clearly adds to the literature. However, similar to other studies, it's hard to generalize across all patients and all P2Y12 inhibitors. Nice summary of this in Eurointervention (eurointervention.pcronline.com/article/one-mo…).

With previous trials such as SMART-DATE & STOPDAPT-2 STEMI suggesting potential harm with shorter DAPT in STEMI, & with the current population consistent of only 30% STEMI, how do you feel about extrapolation of this data to your STEMI population?

#CardsJC

How do you think the lack of availability of high-sensitivity troponin in China & Pakistan impacted the results of this study?

#CardsJC

And just as a quick reminder! Here is a great infographic reviewing BARC score for bleeding 🩸 by Kate Alta 👩🏼‍🦰

How do you think the inclusion of non-major (BARC 2) bleeding in primary outcome impacted results?

#CardsJC

Do you think these outcomes would be reproducible with other, potentially less potent, antiplatelet agents such as Clopidogrel? 💊

#CardsJC

To the Results!🔥

Significantly lower risk of bleeding without increased MACE was observed in ticagrelor monotherapy group compared to DAPT group

Do these results surprise you?

#CardsJC

With 88% of enrolled patient being from China, with known differences in comorbid risk factors between races, are you concerned about the generalizability of these results?

#CardsJC

Now let's take a peek at some baseline characteristics

Any thoughts specifically looking at:

👩 25% female representation?

🫀 NSTEMI/UA to STEMI ratio?

🫀 70% with single vessel disease?

#CardsJC

To the Trial!

Let us look at our inclusion criteria

Does anything catch your eye? 👀

#CardsJC

Want to make the conversation easier to follow? 🎥Watch this great tutorial on how to use tweetdeck.twitter.com made by Daniel Ambinder, MD #CardsJC

ULTIMATE-DAPT set out to assess if ticagrelor alone vs ticagrelor & aspirin could ⬇️ major bleeding🩸risk without ⬆️ risk of MACE 🫀

Which will win the ultimate battle? 🥊😉

#CardsJC

A nice review of #ULTIMATEDAPT trial by Ramy Doss

If you didn’t get a chance to read the original ULTIMATE-DAPT trial, please check out our visual abstract and article summary! #CardsJC

cardionerds.com/ultimate-dapt-…

Join us as we discuss the #ULTIMATEDAPT trial with the House of Tausing team this Thursday 05/09/24 at 8 PM Eastern Time !🤓🫀🎉CardioNerds CardioNerdsJC #CardsJC

Join in, ask & answer Qs, learn from our amazing content experts 👇🏾and CardioNerds Faculty, FITs & Family ❤ #CardsJC

Poonam Velagapudi
Ajar Kochar
Karol Watson
Moussa Mansour
Oluwaseyi Bolorunduro
Ali Nsair, MD
Rani Hasan
Ty Gluckman
Mukta Srivastava
Melissa Tracy
Eugene Yang
Seyi Bolorunduro MD MPH

We are Emily Lee Ramy Doss Maryam Barkhordarian @Dhruv_mkrishnan, CardioNerds Academy Fellows #HouseTaussig , interns Adriana C. Mares Chelsea Amo Tweneboah, MD, chief Rawan Amir

We'll be your hosts for this Journal Club📚, we have no COI. We want to hear from you, so tag your tweets with #CardsJC .

It's almost⏲️for this months #CardsJC !

Come hang out with us to discuss one of the🔥trials of the year, #ULTIMATEDAPT with this stellar group of nerds!

When🕗: Tomorrow 5/9, 8PM EST.

We can't wait to see you there!!
#CardsJC

Congratulations to our third-year fellow Ahmed Teebi, MD MPH🗝️ 👏🏼👏🏼👏🏼

🔥Keynote lecture on ‘Coronary Microvascular Disease in Women’ 🔥by Nishtha Sareen MD MPH FACC FSCAI at the resident-led Women’s heart symposium at Ascension Providence this morning!🫀👩 Abdulghani Sankari Ascension Providence Cardiovascular Fellows