Happy to share Laura Cacciaguerra et al study of #MOGAD lesion changes during attacks: ➡️ 10% of attacks have an initial normal MRI (radiologic lag) ➡️ MRI more dynamic than in #MS or #NMOSD with T2-Lesions often appearing & sometimes resolving within attacks👇neurology.org/doi/10.1212/WN…

Check out this great case by Drs Syc-Mazurek & Zhao-Fleming Mayo Clinic Neurology Residency reporting #MOGAD with melanoma exacerbated by immune checkpoint inhibition ➡️ IL-6 blockade with tocilizumab worked perfectly for #MOGAD without reducing anti-tumor immune response👇neurology.org/doi/10.1212/NX…

And I have the best mentors in the world 🙌🙌😉absolutely enjoyed my time here and very excited to be staying for my next chapter!

Thanks to the American Academy of Neurology for the opportunity to present our work on “Frequency, Challenges, and Potential Etiologies of Increased Intracranial Pressure in MOGAD” at the #AANAM #AAN2024 🧠🧩 John J. Chen, MD, PhD Eoin Flanagan
The 🐻 seems interested!

Delighted to share our study on CSF MOG-IgG! Testing in CSF was useful when: ➡️ A suspicious phenotype but negative serum MOG-IgG ➡️ Low positive serum MOG-IgG with diagnostic uncertainty as dual positivity in serum & CSF more likely to be #MOGAD 👇onlinelibrary.wiley.com/doi/10.1002/an…

Acute Optic Neuropathy in Older Adults: Differentiating Between #MOGAD Optic Neuritis and Nonarteritic Anterior Ischemic Optic Neuropathy bit.ly/43FYFE9

#NAION #NeuroTwitter

Absolutely thrilled to be joining Mayo Clinic Neurology Residency 😊😊!!
This would have been impossible without all the support along this journey from my amazing family, friends, and mentors John J. Chen, MD, PhD Eoin Flanagan, Dr. Pittock, and many others from Siriraj

Pleased to share our new publication! - Peripheral nervous system manifestations of MOG antibody associated disease

Divyanshu Dubey Eoin Flanagan Yahya Abdulrahman

onlinelibrary.wiley.com/doi/10.1002/ac…

📣 AAN Summer Conference on Autoimmune Neurology July 19-20 in Atlanta ➡️ 48 hours of incredibly high yield information 🧠
Mark Your Calendar now . Details coming soon - Sign up to be the first to know:
aan.com/events/summer-…

Our critical appraisal of how the future might look…..it’s a hypothesis with - in my view - ever increasing data to support the concept…..Looking Beyond Syndrome-Based Criteria for Autoimmune Encephalitis w ⁦Eoin Flanagan⁩ &⁦Adrian Budhram jamanetwork.com/journals/jaman…

Happy to share our review of current evidence on monoclonal antibody therapies for #NMOSD and #MOGAD including ongoing phases 2 & 3 clinical trials John J. Chen, MD, PhD

journals.lww.com/sjop/abstract/…

Presented our work at #MSMilan2023 #ECTRIMS
Saw an older patient with unilateral optic disc swelling? Don’t forget MOGAD!
Clinical presentations remain the most important clues to differentiate MOGAD optic neuritis from ischemic optic neuropathy 👁️ John J. Chen, MD, PhD Eoin Flanagan

This study demonstrates that T2-lesions in MOGAD usually resolve within 1 year and follow-up MRI at 6–12 months showing resolution of all or most T2-lesions can help support a #MOGAD diagnosis over competing etiologies. bit.ly/46vX0B2

#NeuroTwitter

Wonder what happened at UMNOG this year? Here is a recap John J. Chen, MD, PhD

➡️Proceedings of the 45th Annual Upper Midwest Neuro-Ophthalmology Group Meeting, 21 July 2023: Neuro-Ophthalmology: Vol 0, No 0 tandfonline.com/doi/full/10.10…

1/6 Happy to share Laura Cacciaguerra et al review on #MOGAD & #NMOSD

It focuses on imaging differences including with #MS

Highlights difference between attack & remission MRI’s

Some useful cartoon images included

See 🧵 👇

neurologic.theclinics.com/article/S0733-…

AMA Language, Respect, and the Medical Profession - Mayo Clinic Proceedings mayoclinicproceedings.org/article/S0025-…

So many interesting talks and amazing discussions! Learned a lot 🧠👁️

Delighted to share this collaborative effort led by Andy Solomon reviewing MS differential diagnosis ➡️ much to update since the prior version in 2008 ➡️ Lots of clinical, imaging & laboratory pearls for practicing neurologists Georgina Arrambide Wallace Brownlee 👇 thelancet.com/journals/laneu…

Picture Quiz—An 85-year-old man with a 5-day history of persistent fever and severe neck pain presented to hospital. No bacteria were identified in the culture test including cerebrospinal fluid. What is the diagnosis? thelancet.com/doi/story/10.1…