Organic Process Research & Development
@OPRD_ACS
A communication tool between industrial, academic, and research institute scientists and engineers to promote chemistry relevant to advancing new applications.
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https://pubs.acs.org/oprd 31-01-2019 19:19:58
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A new Virtual Symposium! Sponsored by ACS Organic Division + Royal Society of Chemistry + SCI – Where Science Meets Business💡 and supported by Organic Process Research & Development. Globally available on June 11. Featuring Oliver Ring Oliver Ring and Sarah Reisman Sarah Reisman
YouTube: zurl.co/uRSx
Zoom: zurl.co/ytYH
🌐 Call for Papers: Industrial Organic Synthesis
Share your research with J Org Chem/Org Lett or Organic Process Research & Development for a chance to be featured in a new special issue focusing on sustainable solutions in the chemical industry. Learn more: go.acs.org/91i
Delighted to share our latest research contribution in flow biocatalysis, published in Organic Process Research & Development ACS Publications! The work is also featured in 'Flow Chemistry Enabling Efficient Synthesis 2024' special issue. 1/n
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In the second Organic Process Research & Development from #PfizerChemistry UK Sandwich process dev teams on a key benzimidazole fragment they improve on the synthesis even more - producing >1.5 metric tons!!!
Paper 2: doi.org/10.1021/acs.op…
Wonderful Organic Process Research & Development paper from #PfizerChemistry Sandwich UK folks on development of an oncology candidate - not only a cool use of Meldrum's acid but an absolutely WICKED cool aza-indazole formation - that one's going in the tool box for sure
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Discover the power of mechanistic modeling for #oligonucleotide #IEX #chromatography with a predictive simulation model and step-by-step methodology for process development pubs.acs.org/doi/10.1021/ac…. From Kobl and colleagues ypsofacto.com
A Shionogi Team has unlocked the secrets of Baloxavir marboxil! They are delighted to share details in a three-part Organic Process Research & Development series unraveling an innovative manufacturing process for this anti-flu drug:
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'Organic Solvent Nanofiltration in Pharmaceutical Applications' from Organic Process Research & Development (Organic Process Research & Development) is currently free to read as an #ACSEditorsChoice .
📖 Access the full article: go.acs.org/8MZ
Not only was it #SolarEclipse2024 today and UCONN is in the Finals tonight...
But its ALSO...
Organic Process Research & Development Items of Interest Day!!!
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Real nice #ChemCollabs here between Vertex Pharmaceuticals Omegachem and Concept Life Sciences out in Organic Process Research & Development making naphthyridones while avoiding hazardous reagents - shout out to my former colleages Jeff Sperry and Dan Richter for a cool paper!
We are pleased to recognize our most-read recently published Organic Process Research & Development articles over the past month--please have a look at what others are finding interesting
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Streamlining catalysis screenings on a shoestring: Fleck and colleagues at Merck Electronics Merck Electronics take a look at a simple software solution to facilitate catalysis screenings and ease the bottleneck of solid dispensing. Learn more: pubs.acs.org/doi/10.1021/ac…
Fantastic work by my #PfizerChemistry UK Process colleagues on enabling a Cu-coupling of a phenol and aryl-Br/CO2H - really great look into reaction design, scale up, solid form and so many details key to proper work on scale Organic Process Research & Development #OPRDasap
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Stay informed on the latest research covering #organic and #organometallic #chemistry . Read wide-ranging collections covering a broad range of topical areas. go.acs.org/8Bb
2,5-Dihydro-1H-pyrrol-3-yl Boronic Derivatives: Multigram Synthesis and Coupling Reactions (Organic Process Research & Development): pubs.acs.org/doi/10.1021/ac… (@DrGregor2).
During the initial discovery work on these compounds, the ketal/dioxolane formation was a real challenge...
Huge Kudos to our #PfizerChemistry UK process dev colleagues for amazing work developing a neat route - now out in Organic Process Research & Development
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