🚨New Urine Test for High-Grade #prostatecancer 🚨

MyProstateScore 2.0 (MPS2 and MPS2+)

At 95% sensitivity for GG2:
✨ Can📉 unnecessary biopsies by 35-42%

Negative predictive value:
✨≥GG2 - 95-99%
✨≥GG3 - 99%

👏 Jeff Tosoian, MD, MPH

▶️JAMA Oncology link: tinyurl.com/25yzhfdd…

Heart breaking that this disease afflicts one to whom we all owe so much. Best wishes for a full recovery! PCF Science

Just in 👉A comprehensive review of PARPi+ARPI combos in 1st line mCRPC #ProstateCancer 👇 by Rana McKay Alicia Morgans, MD, MPH neal shore et al. OPEN access link👉 tinyurl.com/4kajr2h3 OncoAlert UroToday.com PCF Science

grateful to have received the DoD EIRA to continue my research in understanding prostate cancer treatment resistance . Many thanks to my supervisor Amina Zoubeidi, @UBCMedicine, Vancouver Prostate Centre. Excited for whats ahead!

Science in Vancouver PCF Science

Just published concurrently with an #AACR24 poster—
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in #ProstateCancer , by Yaru Xu, Ping Mu 🇺🇦 et al.
bit.ly/3Ucp3C8
PCF Science UTSW Simmons Cancer Center AACR

A nice and useful work in #prostatecancer from ⁦Massimo Loda⁩. The authors showed that DNA repair–blocking drugs can be enhanced through FASN inhibition, which may ⬆️the efficacy of PARP inhibitors in patients with #CRPC . ⁦⁦PCF Science⁩ science.org/doi/10.1126/sc…

It’s a wrap! I had a fantastic time at the #AACR2024 and left feeling inspired! Thanks to the organizing committee for the opportunity to chair and present our research in the AOS07 session! I am looking forward to AACR2025.

#ProsTIC24 ProsTIC #Melbourne highlights

youtu.be/DutkLI0GAUQ

Interviews with Ken Herrmann Howard Soule participants from Philippines, China, Spain & Mexico

Thanks Declan Murphy for capturing the atmosphere
on this outstanding #GUcast episode... don't forget to…

.Prostate Cancer Foundation is proud to support these incredible 2024 AACR-Prostate Cancer Foundation Scholar-in-Training Award Recipients!

Check out their posters!

Preliminary results of ProScreen trial: RCT, n=60,745 in 🇫🇮, comparing invitation to screen (PSA➡️4K➡️MRI) vs no invitation

jamanetwork.com/journals/jama/…

15-year results of the CAP #ProstateCancer screening trial. n=415,357 in 🇬🇧 randomized to single invitation for a PSA test vs no invitation

Richard Martin

jamanetwork.com/journals/jama/…

In JAMA this weekend: Two major #ProstateCancer screening publications

Richard Martin Caroline Moore Matt Cooperberg Hashim U. Ahmed Andrew Vickers Andreas Røder Matt Hobbs PCF Science
👇🏼

👉How do you improve the only FDA approved cellular therapy for #prostatecancer ?

✅out our newest work in Cancer Immunology Research #AACR24

👉First deep analysis of Sip-T & est'd preclinical model. thx 2 Brian Van Tine Fehniger Lab Pachynski Lab

aacrjournals.org/cancerimmunolr…

🚨Update from RADICALS-RT🚨

Annals of Oncology

Early salvage vs adjuvant radiotherapy for unfavorable-risk #prostatecancer

🗓️Median of ~8 years follow-up

☢️% receiving any RT:
Adjuvant - 93%
Vs
Salvage - only 39%🥳

⚖️No difference in oncologic outcomes

Open access:…

Our new paper was published online today at Cancer Discovery. If you are attending #AACR2024 , please visit our poster today to hear the first author, Dr. Yaru Xu, discuss her fascinating work. PCF Science UTSW Simmons Cancer Center

Don’t underestimate the beyond project impact of fellowships. Academy of Medical Sciences Prostate Cancer UK NIHR Research Medical Research Council PCF Science Wellcome have supported me over the past 10 years. Thank you does not seem enough.

The Agency has given us the 'study may proceed' for our first-in-human STEAP1 CAR T trial for mCRPC tinyurl.com/u6fc59tx led by Jessica Hawley MD MS Fred Hutchinson Cancer Center! Truly a collaborative effort to tackle prostate cancer! PCF Science CDMRP Institute for Prostate Cancer Research NCI Treatment

Congratulations, Jessica Hawley MD MS Fred Hutchinson Cancer Center!! Prostate Cancer Foundation PCF Science

🚨Just out in JAMA 🚨

📢Simultaneous publication of TWO #prostatecancer screening trials

👉ProScreen trial: tinyurl.com/23hj7mvu
👉CAP trial: tinyurl.com/bddzbc3m

#EAU24 Amer. Urol. Assn. JAMA Network Prostate Cancer Foundation PCF Science YUO Society of Urologic Oncology European Association of Urology (EAU) EAU Edu Platform UROONCO…

The Lancet Commission: prostate cancer fatalities to double in next 20 years, even with ongoing public health initiatives
The urgent call to action? Accelerate advanced diagnostic tools and more effective treatments

youtube.com/watch?v=9uICBf…

Thanks Holly Edwards-Smith for covering…