In today's #readoftheweek 📚, learn how soluble urokinase plasminogen activator receptor, as a surrogate of hepatic inflammation, may be used to stratify care in patients following TIPS insertion.

Read here this #openaccess JHEP Reports article: jhep-reports.eu/article/S2589-…

🙏

Congratulation Jordi. You deserve it. 👏🏻👏🏻👏🏻

🔊Valdig Group study ‼️
➡️Abdominal surgery & portal cavernoma:
❌high-risk of bleeding🩸
❌high-risk of portal hypertension complications
✅same risk of grade ≥3 postop. complication & death

⚠️when ascites
⚠️when non-wall, non-cholecystectomy surgery

pubmed.ncbi.nlm.nih.gov/38683626/

After Professor Vicente Arroyo directorship, we warmly welcome new Eur. Fdn. for the Study of Chronic Liver Failure Director, Professor Richard Moreau, who joins the newly established Governing Board. Learn more about his motivations and vision for the next 3 years: efclif.com/foundation/new…

Our #SteeringCommittee Meeting’s already wrapped up! The morning was filled with 🔥 news: From understanding AD at systems levels to project’s #dissemination progress, and our #ethics & #socioeconomics work package.

DECISION’s enthusiastic about what’s next! 💪
#cirrhosis

After a warm welcome from Rautou Pierre-Emmanuel we dove directly into the sessions & had inspiring talks about
❇️epigenetic signatures
❇️single-cell transcriptomics
❇️Serum microRNA profile
❇️inflammatory protein mediators
❇️whole-blood transcriptomics #multiomics in #cirrhosis

#myUEGcommunity #UEGResearch #weareUEG

Silvio Danese Marianna Arvanitaki Dragomir Dardanov @mariettaiacucci @melchiorchloe @rautoue @lissyderidder @bohumilseifert @reenasi25801469 @annemiekesmet @mzorniak

✅ Most interesting study! It shows the explanation for the early presinusoidal component in portal hypertension (PH) in cholestatic liver disease.
➡️ Please note that obliteration of portal venules also occurs in viral cirrhosis!
@BavenoCooperation …thsocjournals.onlinelibrary.wiley.com/doi/abs/10.100…

So excited! 🌟 Later this week, our 9th Steering Committee (SC) Meeting will take place in Münster 🇩🇪, hosted by Uniklinik Münster. During the meeting, we'll be discussing the project's progress, its achievements so far, & plan ahead for the next months to come.
#ACLF #cirrhosis

⭐️ I am thrilled to announce that the new and unique book “Sinusoidal cells in liver diseases” is finally out❗️

25 chapters - 562 pages of updated translational & clinical science focused on the cells living in the sinusoidal milieu

Get yours here!
🔗 shop.elsevier.com/books/sinusoid…

🔊Just out: an overview of prognosis algorithms for acute decompensation of cirrhosis and ACLF
🤔how these scores were built❓
🤔how were they validated❓
🤔what is their accuracy❓
🤔what are the perspectives to improve them❓
➡️all the answers are here:
doi.org/10.1111/liv.15…

Bravo à Beaujon, à toutes ses équipes 🚀 un honneur d’en faire partie 🙏

❕Expert opinion on bleeding risk from invasive procedures in cirrhosis

🔓 #OpenAccess at 👉jhep-reports.eu/article/S2589-…

#LiverTwitter
#cirrhosis
Rautou Pierre-Emmanuel

I’m happy to present you the issue of April 2024 of the Journal of Hepatology with outstanding papers

Don't miss Coordinator of Decision4Liver Rautou Pierre-Emmanuel from CRI - Centre de Recherche sur l'Inflammation CNRS Biologie on his state-of-the-art lecture 'Management of invasive procedures in patients with #cirrhosis ' today at PHC 2024

A 30-year-old man referred for hepatomegaly and with a “mosaic” enhancement pattern at the arterial phase at CECT.
History of bone marrow transplantation 9 years earlier.
What is your diagnosis?
See more here: authors.elsevier.com/a/1imHYcOnAQzZt

Today’s #readoftheweek focuses on bleeding risk associated with invasive procedures in patients with #cirrhosis .

Read here this🔓 #openaccess JHEP Reports article: bit.ly/3wQJrQn

🙏 Rautou Pierre-Emmanuel et al.

📣Research challenges the view of decompensated #cirrhosis .
Acute & Non-Acute Decompensation pathways offer nuanced perspectives. This review explores these insights, guiding future clinical approaches. #LiverTwitter Jonel Trebicka Uniklinik Münster
🔓 onlinelibrary.wiley.com/doi/10.1111/li…

CRI - Centre de Recherche sur l'Inflammation Hôpital Beaujon AP-HP Rautou Pierre-Emmanuel

Just out in JHEP Reports
In patients with cirrhosis undergoing liver transplantation, HVPG predicts:
➡️ major intraoperative bleeding
➡️ postoperative acute renal failure
➡️ vasopressor infusion duration
➡️ ICU length of stay

doi.org/10.1016/j.jhep…