Stray Kids I found the photo from the waterfall we crashed on. It was spring 2006, so I was 13. Sadly I havent had the opportunity to go white water rafting again since then. Hopefully I will.
Dr Claire Taylor But the similarities and differences between my symptoms and those of post-infection ME cases make a lot of sense with the metabolic changes found in 2021.
Dr Claire Taylor I'm waiting on the results to know exactly what the genetic disorder is, but it is probably something on the methionine metabolic pathway that was mild and worsened by the PLP deficiency.
Levothyroxine induced PLP deficiency isn't recognized, but there's supporting evidence
Dr Claire Taylor If other viruses or infections can trigger similar metabolic changes, then other post-infection ME could be the same.
I dont have post-infection ME. My own case seems to be a combination of a genetic disorder and a funtional pyridoxal phosphate deficiency cause by levothyroxine
Dr Claire Taylor The results would combine the symptoms of glycogen storage diseases, deficiencies of pyridoxal phosphate and magnesium, and high oxidative stress. Normal micronutrient tests would be 'normal' but patients would have higher demand than healthy patients.
Dr Claire Taylor A recent study on muscle biopsies in long covid patients plus a 2021 study on changes to the glycolytic pathways during infection (and may continue after) has made me think that widespread, functional micronutrient deficiencies may develop from infection.
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