Our c-di-GMP sensor story is finally out in Nature Communications: rdcu.be/dHsEh. Including new data demonstrating cdGreen2 as a convenient tool to study DGC and PDE activity in vitro. Great collaboration with Simon van Vliet and Maier Lab!

Ever wondered how different caspases select their substrates? Turns out, they have their own styles. Check out our study: cell.com/immunity/abstr… Immunity Cheers to the fantastic teamwork! Jonathan Kagan Kay Lab Prof. Hao Wu. 🥳🧵(1/7)

UK increases in #pertussis , #AMR concerning and potentially preventable (also #H5N1 ). #StrepA is another concern globally-but prev neglected by UK science. Today 3 papers on X! Need a #StrepA vaccine
rdcu.be/dHxGA
doi.org/10.1101/2024.0…
thelancet.com/journals/lanmi…

Great opportunity to present your work👇 cellular microbiology aficionados. Please spread the word and see you all in Sheffield!

The Acinetobacter Conference 2025 will be in Niagara Falls. We have a website!!

events.faseb.org/event/biology-…

We're hiring 2 predoctoral fellows! We offer: 1-yr contract, ≈50 kCHF gross salary, cutting-edge mol-biol training, authorships to papers, opportunities to enter a PhD program after 1 yr. Only open to EU/EFTA holders of an MSc degree. Only email applications, no DM.

1/12 New preprint from the C. LESTERLIN - TacC LAB lab ! The tale of a sunday side project that snowballed : A palette of bright and photostable monomeric fluorescent proteins for bacterial time-lapse imaging biorxiv.org/content/10.110…

Our first arrayed CRISPR-a screen with T.gonfio is out. Kathi Ging mapped the complete transcriptional landscape of glucocerebrosidase. If you have nothing else to do this weekend, please read it and give me critical feedback! biorxiv.org/content/10.110…

Fun - fun - fun 🧫
Thanks C. LESTERLIN - TacC LAB Lesterlin lab for sending around the E. coli w/ plasmids for your new FPs 🤩
See their preprint here:
biorxiv.org/content/10.110…

After countless requests, we're thrilled to introduce PK Mito Orange FX - a fixable variant of PKMO. PKMO FX allows immunolabeling and CLEM approaches.

Happy to have contributed to this project led by Zhixing Chen and Christian Jüngst.
#mitochondria

pnas.org/doi/10.1073/pn…

🔬 Mélanie Hamon melanie hamon explore les interactions bactériennes 🦠
Lauréate 'Chair d'excellence' #France2030 son projet vise à comprendre les mécanismes des infections invasives pour découvrir de nouveaux traitements thérapeutiques
Ministère Enseignement supérieur et Recherche
ANR
Secrétariat général pour l’investissement

Towards planet-compatible chemicals! Check out our latest research where we use E. coli to convert methanol to industrially relevant molecules.
#ClimateCrisis #GreenChemicals #syntheticbiology
nature.com/articles/s4192…

Exciting news! Our latest preprint is out, showcasing the work of Nicolas Flaugnatti on T6SS & capsule in Acinetobacter baumannii.
Congratulations Nico! 🍾🥳
🧵below .... 1/x

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii biorxiv.org/content/10.110…

Love host-pathogen interactions? I have TWO MRC-funded postdoc positions to investigate IFNs and Salmonella. I’m looking for a cell biologist and an immunologist. Links below, reach out if you have any questions-Please RT!
tinyurl.com/vhparsu7
tinyurl.com/3fhp9yz4

Congratulations to Miro (Miro Plum), Christy (@christy_chc), Patricia and others on a beautiful paper showing #T6SS role in spreading of Burkholderia thailandensis between infected cells:
authors.elsevier.com/sd/article/S19…

🦠 Cave Bacteria: Illuminating a new path to multicellularity

​​A new species of multicellular bacteria found in a cave offered clues as to how multicellular organisms arise. 8/13
elifesciences.org/articles/83296…

Overall, absolutely worth the time and effort for an amazing day but I’ll be retiring my part-time party planning career and back to full-time science on Monday - proudly wearing the CMBI2 signature green lab coat 🥼

Tang Lab, Oxford Carmen Beuzon Salcedo Lab Charlotte Odendall Sophie Helaine Teresa Thurston These women have been instrumental in laying the groundwork that has shaped my experience as both a scientist and as a woman in STEM, highlighting the importance of dedication and .... persistence! Carmen Beuzon Salcedo Lab Charlotte Odendall Sophie Helaine Teresa Thurston

Tang Lab, Oxford The afternoon consisted of talks from some inspiring women who have come through the lab and have gone on to have insanely successful careers all over the world Carmen Beuzon Salcedo Lab Charlotte Odendall Sophie Helaine Teresa Thurston

The day started with amazing talks by Tang Lab, Oxford , Prof Michael Hensel and Prof Jeremy Brown reminiscing about some of the early days in the Holden lab.