Our latest work is out now in Cell Genomics. Hillary Layden and team use the dTAG system and deep genomic analysis to determine how wild-type and mutant FOXO1 control transcription in DLBCL. cell.com/cell-genomics/…

Nature research paper: Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF go.nature.com/4aA7Rfz

Excellent review by Saurav Kumar and Behnam Nabet highlighting recent innovative approaches for chemically controlled protein relocalization. Thanks for also mentioning our self-localizing ligand approach!

Are you interested in strategies to control the spatial localization of your favorite protein at will? In our review, Saurav Kumar and I discuss the exciting development of chemical inducers of proximity to control subcellular protein localization. authors.elsevier.com/a/1ikNC3S7Zk9Z…

It was a pleasure to highlight the recent innovative studies from the labs of Stuart Schreiber and Matthew Meyerson (NICE approach), Steven Banik (TRAM approach), and Dan Nomura (covalent recruiters of 14-3-3 proteins).

The Berger lab is hiring! We have openings for post-docs and research techs right now! Feel free to apply or just reach out to chat. Our lab uses functional genomics to map cancer genotype to phenotype at scale. Come join us! Links in thread

Beautiful summary of our work! Thanks Fred Hutchinson Cancer Center for selecting our work for the spotlight
fredhutch.org/content/www/en… via Fred Hutchinson Cancer Center

Excited to see our latest paper featured on the eLife Cover Fred Hutchinson Cancer Center eLife - the journal

Cas activates Inactive integrin.
Inactive integrin activates Active Integrin.
Cas activates Crk via binding.
Crk activates Rac1 via binding.
Rac1 acti... biofactoid.org/document/ac279…

My post-doc work is now online in #eLife . In this work, we show a two-step model for the initiation of integrin activation that starts with Cas clustering and phosphorylation.
doi.org/10.7554/eLife.… eLife - the journal

Received NOA for R00, so lab is officially NIH-funded! Seeking postdocs interested in the broad areas of chromatin dynamics and transcription regulation. Fully funded positions available immediately. DM/email ([email protected])/ apply now at brahmalab.org. Please RT

Fred hutch with Helix Cloud Fred Hutchinson Cancer Center

My Post-Doc work on a long-standing question about Integrin activation and cluster formation is now available as pre-print. Comments and suggestions are welcome! Fred Hutchinson Cancer Center Hutch Basic Sciences #Cooperlab
biorxiv.org/content/10.110…

Thanks Sue for the gift!!.Hutch Basic Sciences

This #FridayNightTalks Saurav Kumar from the Cooper Lab is sharing their research on the regulation of integrin by Cas during cell migration and Stephanie Dobersch from Human Biology’s Kugel Lab is discussing novel functions of LIN28B in pancreas cancer. Can’t wait!

The Lehrbach lab Fred Hutchinson Cancer Center is hiring! We're looking for a postdoc to join us in beautiful Seattle and help unravel the mysteries of proteostasis. Please retweet.

careers-fhcrc.icims.com/jobs/19723/job

Excited for this year's Basic Sciences Retreat! Things kick off today with a virtual poster session. Can’t wait to chat with all of the presenters and learn about everyone’s latest research!

A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics biorxiv.org/content/10.110…

Bill Earnshaw discovered CENP-A and Margolis was the one who showed it was a histone with unique properties.....colleagues tell me that many people did not believe him that it was a histone.....

Mechanisms of stretch-mediated skin expansion at single-cell resolution | Nature. Wonderful collaboration with Ben Simons, Thierry Voet and Alejandro Sifrim. Thanks to all for making this possible. 7 years of work from its conception ! Fund by ERC EXPAND nature.com/articles/s4158…