GPT-4 performed about the same (and sometimes better) than Israeli doctors on the 2022 Israeli medical board residency examinations.

Not sure how I feel about this.

ai.nejm.org/doi/full/10.10…

Time for an update for our IBD caller for ancient DNA! Today we released ancIBD v0.6 ancibd.readthedocs.io/en/latest/inde…
We added two new functions: 1) IBD2 calling and 2) IBD calling on X chromosomes

A study of the accuracy of polygenic scores for 457 diseases in 276k genotyped individuals from a hospital in Taiwan.

nature.com/articles/s4146…

Poseidon - A framework for archaeogenetic human genotype data management biorxiv.org/cgi/content/sh… #biorxiv_genetic

No words can describe how evil Netanyahu and his government are. The pain they have inflicted on millions of Israelis and Palestinians in less than 1.5 years is unimaginable. And now they started a war with Iran. Pray for us.

1/ What do you think about sequencing the entire genetic code ( #genome ) of babies at birth?

👶 🧬 🔍

A thread based on our The BMJ paper

bmj.com/content/384/bm…

APRIL 19, 1pmET! Join HC CEO Vardit Ravitsky, host Dr. Insoo Hyun, & instructor Lauren Walsh in this interactive webinar as they wade through the thicket of the promises and perils of polygenic embryo screening.
Cosponsors: Museum of Science Harvard Medical School Center for Bioethics
thehastingscenter.org/hastings-cente…

A preprint from the 23andMe Research Team exploring the multi-ancestry genetics of diarrhea during acute Covid in which we find evidence that IBS subtypes influence risk.

Kudos to the 1st author, Ninad Chaudhary Ninad Chaudhary, a postdoc in the Research Team!🙌medrxiv.org/content/10.110…

'Blended Genome Exome (BGE) as a Cost Efficient Alternative to Deep Whole Genomes or Arrays'

Low-coverage (2-3x) whole genome with a 30-40x exome.
biorxiv.org/content/10.110…

🧬HAAM Summer School🧬 17-19 June 2024, online and *free*
💻 3 days with all things aDNA, with theoretical + practical sessions & round tables:
1⃣ NGS data processing & Ethics
2⃣Genetic relatedness
3⃣Pop gen analyses
Applications will open soon!
haam-community.github.io/projects/haam_…

Found a shared genomic segment (IBD) of a modern genome with a Medieval individual? It does not imply an exceptional genealogical connection, really!
Read more in our short The Conversation piece (inspired and led by Shai Carmi) ⬇️
theconversation.com/dna-says-youre…

Are there any articles on the ethics of sequencing the DNA of *named* historical individuals?
The number of such papers is rising quickly and it seems to have become a norm. Maybe OK, but it wouldn't hurt to have some debate.

It seems like it's the time of the year for coalescent hidden Markov model preprints:
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…

(ProbGen?)

A structured coalescent model reveals deep ancestral structure shared by all modern humans biorxiv.org/cgi/content/sh… #biorxiv_genetic

Excited to share my first PhD publication at #MPRGBiosocial with Laurel Raffington, PhD ! 🚨📜

🧬📚 We examined geographical and historical differences in polygenic associations with educational attainment in East and West Germany around reunification🧬🏛️

biorxiv.org/content/10.110…

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